BDB564474

ROR1 Mouse anti-Human, PE, Clone: 4A5, BD

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB564474-Each-of-1 In Stock ₹ 22,428.00

BDB564474 - Each of 1

₹ 22,428.00

In Stock

Quantity

1

Base Price: ₹ 22,428.00

GST (18%): ₹ 4,037.04

Total Price: ₹ 26,465.04

Antigen

ROR1

Classification

Monoclonal

Conjugate

PE

Formulation

Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen

Human ROR1 cDNA

Quantity

50 Tests

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications

Flow Cytometry

Clone

4A5

Description

Neurotrophic tyrosine kinase, receptor-related 1; NTRKR1

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Human

Isotype

IgG2b κ

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Description

  • The 4A5 monoclonal antibody binds to the glycosylated type I membrane protein ROR1 (Receptor-tyrosine-kinase-like Orphan Receptor 1)
  • The ROR1 and ROR2 related proteins are highly conserved evolutionarily and are primarily expressed during embryogenesis
  • ROR1 is not expressed on normal peripheral blood lymphocytes
  • ROR1 is similar to tropomyosin receptor kinase (Trk family) neurotropic receptors and shares a cysteine-rich domain with Frizzled receptors for Wnt-family signaling proteins, which are involved in the regulation of embryogenesis and carcinogenesis
  • Furthermore, there is mounting evidence that aberrant ROR1 expression contributes to human malignancy.