BDB563543
IL-6 Rat anti-Human, PE-CF594, Clone: MQ2-13A5, BD
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB563543-Each-of-1 | In Stock | ₹ 25,409.50 |
BDB563543 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 25,409.50
GST (18%): ₹ 4,573.71
Total Price: ₹ 29,983.21
Antigen
IL-6
Classification
Monoclonal
Conjugate
PE-CF594
Formulation
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen
Human IL-6 Recombinant Protein
Quantity
50 Tests
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications
Flow Cytometry
Clone
MQ2-13A5
Description
IL6; Interleukin-6; BSF-2; CDF; HGF; HSF; IFNB2
Host Species
Rat
Purification Method
Affinity Purified
Regulatory Status
RUO
Target Species
Human
Isotype
IgG1
Related Products
Description
- The MQ2-13A5 monoclonal antibody specifically binds to human interleukin-6 (IL-6)
- IL-6 is a multifunctional cytokine that plays a central role in host defense mechanisms, including hematopoiesis, immune responses (eg, T and B cell activation and differentiation) and acute phase reactions
- IL-6 can be expressed by a variety of cells including monocytes/macrophages, eosinophils, fibroblasts, vascular endothelial cells, bone marrow stromal cells, mesangial cells, hepatocytes, keratinocytes, astrocytes, T lymphocytes, B lymphocytes, and various tumor cells
- IL-6 production is upregulated by cells in response to bacterial products such as lipopolysaccharide, viruses and other pro-inflammatory cytokines such as IL-1, TNF , and IFN-γ
- IL-6 transcription is downregulated by cells in response to IL-4 and IL-10
- The functional IL-6 Receptor (IL-6R) complex consists of two transmembrane glycoproteins, an 80-kDa low-affinity ligand-binding receptor subunit (IL-6Rα/CD126) and a 130 kDa (gp130/CD130) subunit that binds to IL-6-IL-6Rα to form the high-affinity signal transducing complex
- Abnormal expression of IL-6 is related to the pathogenesis of many diseases including neoplastic (eg, multiple myeloma) and autoimmune diseases (eg, rheumatoid arthritis)
- The immunogen used to generate this hybridoma was COS-7 -expressed recombinant human IL-6.