BDB563766

OX40 Ligand Mouse anti-Human, Brilliant Violet 421, Clone: ik-1, BD

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB563766-Each-of-1 In Stock ₹ 27,367.50

BDB563766 - Each of 1

₹ 27,367.50

In Stock

Quantity

1

Base Price: ₹ 27,367.50

GST (18%): ₹ 4,926.15

Total Price: ₹ 32,293.65

Antigen

OX40 Ligand

Classification

Monoclonal

Conjugate

Brilliant Violet 421

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Human

Isotype

IgG1 κ

Applications

Flow Cytometry

Clone

ik-1

Description

CD252; OX40 Ligand; CD134 Ligand; CD134L; TNFSF4; GP34; TXGP1

Immunogen

Human OX40 Ligand Transfected Cell Line

Quantity

50 Tests

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Description

  • The ik-1 monoclonal antibody specifically binds to OX40 Ligand (OX40L) which is also known as CD252 and CD134 Ligand
  • OX40L is encoded by TNFSF4 (Tumor necrosis factor (ligand) superfamily, member 4)
  • OX40L a 34 kDa type II transmembrane glycoprotein that is expressed by dendritic cells, B cells, human umbilical vein endothelial cells (HUVEC) and other types of vascular endothelial cells
  • OX40L serves as a costimulatory ligand by binding to and signaling through OX40 (CD134) which is expressed on activated T cells
  • It also mediates adhesion of activated T cells or OX40-positive transformed cells to vascular endothelial cells
  • Monocyte-derived dendritic cells (MoDC) express OX40 Ligand after stimulation through CD40
  • Ligation of OX40 Ligand expressed by activated MoDC can significantly increase their cytokine production.