BDB564034
CD25 Mouse anti-Human, BUV395, Clone: 2A3, BD
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB564034-Each-of-1 | In Stock | ₹ 41,830.00 |
BDB564034 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 41,830.00
GST (18%): ₹ 7,529.40
Total Price: ₹ 49,359.40
Antigen
CD25
Classification
Monoclonal
Conjugate
Brilliant Ultraviolet 395
Formulation
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen
Human Phytohemagglutinin-activated T Cells
Quantity
100 Tests
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications
Flow Cytometry
Clone
2A3
Description
IL-2R; IL2RA; IL-2Rα; TCGFR; TAC antigen; p55
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Target Species
Human
Isotype
IgG1 κ
Related Products
Description
- The 2A3 monoclonal antibody specifically binds to human CD25, the low-affinity alpha subunit of the Interleukin-2 Receptor (IL-2R α)
- CD25 associates with CD122 (IL-2R β chain) and CD132 (common γchain or γc) to form the high-affinity signal-transducing IL-2R complex
- CD25 is expressed by a subset of peripheral blood lymphocytes including CD4+CD25+ natural regulatory T cells
- CD25 antigen density increases on activated T cells including phytohemagglutinin (PHA)-, concanavalin A (Con A)-, and CD3-activated T lymphocytes
- High levels of CD25 can also be expressed by T lymphocytes from mixed lymphocyte cultures and by human T-lymphocyte leukemia virus (HTLV)-infected T-lymphocyte leukemia lines, for example, HUT-102
- Recombinant IL-2 blocks the binding of the 2A3 antibody to PHA-activated T lymphocytes
- The antibody was conjugated to BD Horizon™ BUV395 which has been exclusively developed by BD Biosciences as an optimal dye for use on a 355nm laser equipped instrument
- With an Ex Max at 348nm and an Em Max at 395nm, this dye has virtually no spillover into any other detector
- BD Horizon™ BUV395 can be excited with a 355nm laser and detected with a 379/28 filter.