BDB564420
CD4 Mouse anti-Human, BB515, Clone: RPA-T4, BD
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB564420-Each-of-1 | In Stock | ₹ 6,230.00 |
BDB564420 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 6,230.00
GST (18%): ₹ 1,121.40
Total Price: ₹ 7,351.40
Antigen
CD4
Classification
Monoclonal
Conjugate
Brilliant Blue 515 (BB515)
Host Species
Mouse
Quantity
25 Tests
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications
Flow Cytometry
Clone
RPA-T4
Description
L3T4; T-cell surface antigen T4/Leu-3; W3/25; CD4 antigen (p55)
Purification Method
Affinity Purified
Regulatory Status
RUO
Target Species
Human
Isotype
IgG1 κ
Related Products
Description
- The RPA-T4 monoclonal antibody specifically binds to CD4, a 59 kDa single-chain transmembrane glycoprotein that is expressed on T-helper/inducer cell populations
- CD4 is also expressed on thymocytes subsets and at lower levels on monocytes and macrophages
- CD4 functions as a co-receptor in MHC class II-restricted antigen-induced T cell activation and as a receptor for human immunodeficiency viruses (HIV)
- This antibody binds to the D1 domain (CDR1 and CDR3 epitopes) of the CD4 antigen and reacts with approximately 80% of thymocytes and 45% of peripheral blood lymphocytes
- RPA-T4 is capable of blocking HIV-1, gp120, and inhibits syncytium formation
- The antibody was conjugated to BD Horizon™ BB515 which was developed exclusively by BD Biosciences
- With an excitation max of 490nm and an emission max of 515nm, BD Horizon BB515 can be excited by the 488nm laser and detected in a standard FITC set (e.g
- 530/30-nm filter)
- This dye provides a much brighter alternative to FITC with less spillover into the PE detector.