BDB564562
Chromogranin A Mouse anti-Human, Unlabeled, Clone: S21-537, BD
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB564562-Each-of-1 | In Stock | ₹ 33,642.00 |
BDB564562 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 33,642.00
GST (18%): ₹ 6,055.56
Total Price: ₹ 39,697.56
Antigen
Chromogranin A
Classification
Monoclonal
Concentration
0.5mg/mL
Description
CGA; CgA; CHGA; Chromogranin-A; CMGA; SP-I
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Target Species
Human
Isotype
IgG1 κ
Applications
Flow Cytometry
Clone
S21-537
Conjugate
Unconjugated
Formulation
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen
Human Chromogranin A Recombinant Protein
Quantity
0.1 mg
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C
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Description
- Chromogranin A (CGA) is a member of the granin family of regulated secretory proteins that are found in secretory granules in endocrine and neuroendocrine cells and released in response to extracellular stimulation
- Intracellularly, granins are important for targeting peptide hormones and neurotransmitters by their ability to aggregate in the low pH, high calcium environment of the trans-Golgi network
- Extracellularly, peptides formed from proteolytic processing of granins regulate hormone secretion
- CGA is a prohormone that can be cleaved into several biologically active peptides, such as pancreastatin, β-granin, vasostatin, catestatin, and parastatin
- β- granin is an N-terminal fragment of CGA, while pancreastatin and catestatin are processed from the central region of CGA
- Cells of the adrenal medulla, anterior pituitary, cerebral cortex as well as beta cells of the pancreas and a variety of tumor cell lines express CGA
- The expression of CGA can be used to monitor the pancreatic differentiation of pluripotent stem cells.