BDB564855
CD369 Mouse anti-Human, Alexa Fluor 647, Clone: 15E2, BD
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB564855-Each-of-1 | In Stock | ₹ 33,998.00 |
BDB564855 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 33,998.00
GST (18%): ₹ 6,119.64
Total Price: ₹ 40,117.64
Antigen
CD369
Classification
Monoclonal
Conjugate
Alexa Fluor 647
Formulation
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen
Human Dectin-1 Recombinant Protein
Quantity
100 Tests
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications
Flow Cytometry
Clone
1.50E+03
Description
CLEC7A; CLC7A; BGR; CLECSF12; CANDF4
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Target Species
Human
Isotype
IgG2a κ
Related Products
Description
- The 15E2 monoclonal antibody specifically binds to CD369 which is also known as CLEC7A (C-type lectin domain family 7 member A), Dectin-1 (Dendritic cell-associated C-type lectin 1), or BGR (Beta-glucan receptor)
- CD369 is a type II transmembrane C-type lectin that contains a C-terminal stalk with a carbohydrate recognition domain (CRD) in the extracellular domain, a transmembrane segment, and an ITAM containing cytoplasmic tail
- This protein is highly expressed on dendritic cells
- It is also expressed on B cells, monocytes, eosinophils, mast cells, macrophages, endothelial cells, and is lowly expressed on some subsets of T cells
- CD369 binds to beta-glucan polymers and functions as a pattern recognition receptor in innate immune response to fungal and bacterial pathogens
- The 15E2 antibody can reportedly stimulate dendritic cells to costimulate immune responses.