BDB565156

CD70 Mouse anti-Human, BB515, Clone: Ki-24, BD

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB565156-Each-of-1 In Stock ₹ 29,681.50

BDB565156 - Each of 1

₹ 29,681.50

In Stock

Quantity

1

Base Price: ₹ 29,681.50

GST (18%): ₹ 5,342.67

Total Price: ₹ 35,024.17

Antigen

CD70

Classification

Monoclonal

Conjugate

Brilliant Blue 515 (BB515)

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Human

Isotype

IgG3 κ

Applications

Flow Cytometry

Clone

Ki-24

Description

CDw70; CD27 ligand; CD27-L; CD27L; CD27LG; Ki-24 antigen; TNFSF7

Host Species

Mouse

Quantity

100 Tests

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Description

  • The Ki-24 monoclonal antibody specifically binds to human CD70
  • CD70 is a type II transmembrane glycoprotein and member of the TNF Superfamily
  • CD70 is also known as Tumor necrosis factor ligand superfamily member 7 (TNFSF7), CD27 ligand (CD27-L, CD27L, CD27LG), and KI-24 antigen
  • The CD70 antigen immunoprecipitates as five bands (50, 70, 90, 100 and 160 kDa) under non-reducing conditions
  • CD70 is strongly expressed on Reed-Sternberg cells, some activated T or B cells and Epstein Barr Virus (EBV)-positive lymphoblastoid cell lines
  • CD70 plays roles in the activation, proliferation and differentiation of B cells and T cells including the enhanced production of cytotoxic T cells
  • The antibody was conjugated to BD Horizon BB515 which was developed exclusively by BD Biosciences
  • With an excitation max of 490nm and an emission max of 515nm, BD Horizon BB515 can be excited by the 488nm laser and detected in a standard FITC set (e.g
  • 530/30-nm filter)
  • This dye provides a much brighter alternative to FITC with less spillover into the PE detector.