BDB565391
CD194 Mouse anti-Human, PE-CF594, Clone: 1G1, BD
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB565391-Each-of-1 | In Stock | ₹ 25,409.50 |
BDB565391 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 25,409.50
GST (18%): ₹ 4,573.71
Total Price: ₹ 29,983.21
Antigen
CD194
Classification
Monoclonal
Conjugate
PE-CF594
Formulation
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen
Human CCR4 Transfected Cell Line
Quantity
50 Tests
Primary or Secondary
Primary
Target Species
Human
Isotype
IgG1 κ
Applications
Flow Cytometry
Clone
1G1
Description
CCR4; C-C chemokine receptor type 4; CMKBR4; K5-5
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Gene ID (Entrez)
1233
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
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Description
- The 1G1 monoclonal antibody specifically binds to CD194, also known as the human CC Chemokine Receptor type 4 (CCR4)
- CCR4 is expressed on activated Th2 cells, regulatory T cells, activated NK cells, basophils, monocytes and platelets
- CCR4 is a seven-transmembrane, G-protein-coupled receptor, and is the specific receptor for CC chemokines, CCL22/MDC/Macrophage-Derived Chemokine and CCL17/TARC/Thymus and Activation-Regulated Chemokine
- It has been reported that CCR4 mRNA is expressed mainly in the thymus and spleen
- The human CCR4 gene has been mapped to chromosome 3p24
- The purified form of this antibody has been reported not to be a neutralizing antibody
- The immunogen used to generate the 1G1 hybridoma has been reported to be human CCR4 transfected L1.2 mouse lymphoma cells
- This antibody is conjugated to BD Horizon PE-CF594, which has been developed exclusively by BD Biosciences as a better alternative to PE-Texas Red™
- PE-CF594 excites and emits at similar wavelengths to PE-Texas Red™ yet exhibits improved brightness and spectral characteristics
- Due to PE having maximal absorption peaks at 496nm and 564nm, PE-CF594 can be excited by the blue (488-nm), green (532-nm) and yellow-green (561-nm) lasers and can be detected with the same filter set as PE-Texas Red™ (eg, 610/20-nm filter).