BDB565215
Aiolos Mouse anti-Human, Alexa Fluor 647, Clone: S50-895, BD
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB565215-Each-of-1 | In Stock | ₹ 25,632.00 |
BDB565215 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 25,632.00
GST (18%): ₹ 4,613.76
Total Price: ₹ 30,245.76
Antigen
Aiolos
Classification
Monoclonal
Conjugate
Alexa Fluor 647
Formulation
Aqueous buffered solution containing BSA and ≤0.09% sodium azide
Immunogen
Human Aiolos Recombinant Protein
Quantity
50 Tests
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications
Flow Cytometry
Clone
S50-895
Description
AIOLOS; AIO; IKZF3; ZNFN1A3
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Target Species
Human
Isotype
IgG1 κ
Related Products
Description
- The S50-895 monoclonal antibody specifically recognizes the transcription factor, Aiolos, which is encoded by IKZF3 , IKAROS family zinc finger 3
- Aiolos belongs to the Ikaros family of zinc-finger proteins that includes Ikaros and Helios
- Aiolos can form homodimers or heterodimers with other Ikaros family members
- Multiple Aiolos isoforms have been described
- Aiolos is expressed in committed lymphoid progenitors and mature types of T and B lymphocytes, but is not expressed by hematopoietic stem cells
- Aiolos plays an important role in the control of B lymphocyte differentiation and proliferation and is specifically required for the generation of long-lived, high affinity plasma cells in the bone marrow
- Aiolos is involved in regulating BCL2 expression and controlling apoptosis in T-cells in an IL2-dependent manner
- Aberrant expression of IKZF3 has been implicated with leukemogenesis and certain autoimmune diseases.