BDB565792
CD281 (TLR1) Rat anti-Mouse, Brilliant Violet 421, Clone: TR23, BD
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB565792-Each-of-1 | In Stock | ₹ 24,208.00 |
BDB565792 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 24,208.00
GST (18%): ₹ 4,357.44
Total Price: ₹ 28,565.44
Antigen
CD281 (TLR1)
Classification
Monoclonal
Concentration
0.2mg/mL
Description
Cd281; Tlr1; Toll-like receptor 1; TIL; Toll/interleukin-1 receptor-like
Host Species
Rat
Purification Method
Affinity Purified
Regulatory Status
RUO
Target Species
Mouse
Isotype
IgG2a κ
Applications
Flow Cytometry
Clone
TR23
Conjugate
Brilliant Violet 421
Formulation
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen
Mouse TLR1 Transfected Cell Line
Quantity
50 μg
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Related Products
Description
- The TR23 monoclonal antibody specifically binds to CD281, which is also known as Toll-like receptor 1 (TLR1), or Toll/interleukin-1 receptor-like protein (TIL)
- CD281 is an ∽98 kDa type I transmembrane glycoprotein that belongs to the Toll-like receptor (TLR) family
- CD281 functions as a pattern recognition receptor (PRR) for pathogen-associated molecular patterns (PAMP) that are broadly expressed by microbial pathogens and plays essential roles in innate and adaptive immunity
- In the process of binding microbial ligands, such as triacylated microbial lipopeptides, TLR1 associates with CD282 (TLR2)
- CD281 is expressed on B cells, monocytes/macrophages, and dendritic cells
- CD281/TLR1-deficient mice display impaired production of inflammatory cytokines in response to microbial ligands
- The antibody was conjugated to BD Horizon BV421 which is part of the BD Horizon Brilliant™ Violet family of dyes
- With an Ex Max of 407-nm and Em Max at 421-nm, BD Horizon BV421 can be excited by the violet laser and detected in the standard Pacific Blue™ filter set (eg, 450/50-nm filter)
- BD Horizon BV421 conjugates are very bright, often exhibiting a 10 fold improvement in brightness compared to Pacific Blue conjugates.