BDB566338
CD141 Rat anti-Mouse, PE, Clone: LS17-9, BD
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB566338-Each-of-1 | In Stock | ₹ 22,962.00 |
BDB566338 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 22,962.00
GST (18%): ₹ 4,133.16
Total Price: ₹ 27,095.16
Antigen
CD141
Clone
LS17-9
Conjugate
PE
Gene Alias
Thbd, TM, TRBM, thrombomodulin, fetomodulin, BCDA-3
Immunogen
Mouse LyEnd.5 Cell Membranes
Quantity
50 μg
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification
Monoclonal
Concentration
0.2mg/mL
Formulation
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species
Rat
Purification Method
Affinity Purified
Regulatory Status
RUO
Target Species
Mouse
Isotype
IgG2a κ
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Description
- The LS17-9 monoclonal antibody specifically binds to CD141, also known as thrombomodulin (TM or TRBM) or fetomodulin
- CD141 is encoded by Thbd /and expressed as a type I transmembrane glycoprotein with an N-terminal C-type lectin domain followed by EGF-like repeats
- CD141 is expressed on a variety of cells including endothelial cells, epithelial cells, mesothelial cells, keratinocytes, synovial lining cells, fibroblastic reticular cells, megakaryocytes, dendritic cells, monocytes, macrophages, neutrophils, precursor B cells, and hematopoietic progenitor cells
- CD141 is required for normal fetal development
- CD141 binds thrombin and this complex can activate Protein C and Thrombin activatable fibrinolysis inhibitor (TAFI), leading to anticoagulant and antifibrinolytic pathway activities R-phycoerythrin (PE) is an accessory photosynthetic pigment found in red algae
- It exists in vitro as a 240-kDa protein with 23 phycoerythrobilin chromophores per molecule
- This makes PE one of the brightest fluorochromes for flow cytometry applications, but its photobleaching properties make it unsuitable for fluorescence microscopy.