BDB566339
TLR6 (CD286) Mouse anti-Human, PE, Clone: TLR6.127, BD
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB566339-Each-of-1 | In Stock | ₹ 32,040.00 |
BDB566339 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 32,040.00
GST (18%): ₹ 5,767.20
Total Price: ₹ 37,807.20
Antigen
TLR6 (CD286)
Clone
TLR6.127
Formulation
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Target Species
Human
Isotype
IgG1 κ
Classification
Monoclonal
Conjugate
PE
Gene Alias
Toll-like receptor 6, CD286
Immunogen
Human TLR6 Transfected Cell Line
Quantity
100 Tests
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Related Products
Description
- The TLR6.127 monoclonal antibody specifically recognizes Toll-like receptor 6 (TLR6), which is also known as CD286
- CD286 belongs to the mammalian Toll-like receptor (TLR) family of pattern recognition receptors that participate in inducing innate and adaptive immune responses to microbial pathogens
- TLR6 is a type I transmembrane glycoprotein comprised of an extracellular domain with a large number of leucine?rich repeats (LRRs)
- Its cytoplasmic region contains a signaling Toll/Interleukin-1 Receptor (TIR) domain
- TLR6 is expressed on monocytes, neutrophils, and some dendritic cells
- In association with TLR2 (CD282), TLR6 recognizes diacylated lipopeptides and peptidoglycans of bacterial or fungal origin
- The ligand-bound TLR2:TLR6 complex transduces responses intracellularly through MyD88 and the NF- B signaling cascade leading to the production of proinflammatory cytokines by responding cells
- R-phycoerythrin (PE) is an accessory photosynthetic pigment found in red algae
- It exists in vitro as a 240-kDa protein with 23 phycoerythrobilin chromophores per molecule
- This makes PE one of the brightest fluorochromes for flow cytometry applications, but its photobleaching properties make it unsuitable for fluorescence microscopy.