BDB610272
p130 [Cas] Mouse, Unlabeled, Clone: 21, BD
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB610272-Each-of-1 | In Stock | ₹ 46,814.00 |
BDB610272 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,814.00
GST (18%): ₹ 8,426.52
Total Price: ₹ 55,240.52
Antigen
p130 [Cas]
Classification
Monoclonal
Concentration
250μg/mL
Formulation
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Immunogen
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Quantity
150 μg
Research Discipline
Cell Biology
Target Species
Canine, Chicken, Human, Mouse, Rat
Isotype
IgG1
Applications
Western Blot
Clone
21
Conjugate
Unconjugated
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Content And Storage
Store undiluted at -20°C.
Related Products
Description
- Description p47 [v-crk] is the product of a transforming gene, v- crk , that was isolated from avian sarcoma viruses
- The v-crk protein is a fusion product of the viral gag protein and a part of cellular crk that includes SH2 and SH3 domains
- v-crk induced transformation increases tyrosine phosphorylation of several cellular proteins, including p130 [Cas]
- p130 [Cas] is tightly associated with v-crk via the SH2 domain of v-crk
- Tyrosine phosphorylation of p130 [Cas] occurs in conjunction with cellular transformation in cells that express v-src or v-crk
- This phosphorylation leads to a change in p130 [Cas] localization from the cytoplasm to the cell membrane and, possibly, to the nucleus
- Since p130 [Cas] also associates with v-src, it may be a v-src substrate.