BDB610385
Adaptin γ Mouse, Unlabeled, Clone: 88, BD
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB610385-Each-of-1 | In Stock | ₹ 25,587.50 |
BDB610385 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 25,587.50
GST (18%): ₹ 4,605.75
Total Price: ₹ 30,193.25
Antigen
Adaptin γ
Classification
Monoclonal
Concentration
250μg/mL
Formulation
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Immunogen
Mouse Adaptin γ aa. 642-821
Quantity
50 μg
Research Discipline
Cell Biology
Target Species
Canine, Human, Mouse, Rat
Isotype
IgG1
Applications
Western Blot
Clone
88
Conjugate
Unconjugated
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Content And Storage
Store undiluted at -20°C.
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Description
- Sorting of integral membrane proteins at various stages of the endocytic and secretory pathways is mediated by vesicular trafficking between a variety of organelles
- Two sorting signals are tyrosine-based and dileucine-based signals that interact with heterotetrameric adaptor protein complexes (AP-1, AP-2, AP-3, and AP-4), which are associated with the vesicle coats
- These coatomers contain two large Adaptin proteins (γ, α, δ, or ε and β1, β2, β3, β4 respectively) that are noncovalently linked to one medium chain (μ1, μ2, μ3, or μ4) and one small chain ( σ1, σ2, σ3, or σ4)
- The AP-1 and AP-3 complexes are involved in protein sorting from the TGN and endosomes, while AP-2 adaptor complexes are involved in clathrin-mediated endocytosis
- Adaptin ? shows more homology with Adaptin α than with Adaptin β
- The conserved regions between Adaptins γ and α could be important for binding to other components of the AP-1 and AP-2 complexes, respectively
- Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blotting