BDB610456

EEA1 Mouse, Unlabeled, Clone: 14, BD

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB610456-Each-of-1 In Stock ₹ 25,053.50

BDB610456 - Each of 1

₹ 25,053.50

In Stock

Quantity

1

Base Price: ₹ 25,053.50

GST (18%): ₹ 4,509.63

Total Price: ₹ 29,563.13

Antigen

EEA1

Classification

Monoclonal

Concentration

250μg/mL

Formulation

Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Immunogen

Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Quantity

50 μg

Research Discipline

Cell Biology

Target Species

Canine, Chicken, Human, Rat

Isotype

IgG1

Applications

Western Blot

Clone

14

Conjugate

Unconjugated

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Content And Storage

Store undiluted at -20°C.

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Description

  • Early endosomes are a major cytoplasmic sorting compartment from which receptors and ligands may be distributed to various sites within the cell
  • Early endosome antigen 1 (EEA1) is a 180kDa hydrophilic peripheral membrane protein present in cytosol and membrane fractions
  • Immunofluorescence studies show that EEA1 colocalizes to early endosomes with transferrin receptor and Rab5, but not with the late endosome-localizing Rab7
  • EEA1 is predominantly α-helical and shares 17-20% sequence identity with the myosins
  • It contains a calmodulin-binding IQ motif and metal-binding cysteine “finger” motifs
  • It is thought that EEA1 is required for vesicular transport of proteins through early endosomes and that these finger motifs are required for this activity
  • Host Species: Mouse Clone: 14 Isotype: IgG1 Species Reactivity [for Features Main]: Human Immunogen: Mouse TRE1 aa
  • 82-179 Immunofluorescence, Immunoprecipitation