BDB610620

Paxillin Mouse, Unlabeled, Clone: 165, BD

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB610620-Each-of-1 In Stock ₹ 50,374.00

BDB610620 - Each of 1

₹ 50,374.00

In Stock

Quantity

1

Base Price: ₹ 50,374.00

GST (18%): ₹ 9,067.32

Total Price: ₹ 59,441.32

Antigen

Paxillin

Classification

Monoclonal

Concentration

250μg/mL

Formulation

Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Immunogen

Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Quantity

150 μg

Research Discipline

Cell Biology

Target Species

Canine, Chicken, Human, Mouse, Rat

Isotype

IgG1

Applications

Western Blot

Clone

165

Conjugate

Unconjugated

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Content And Storage

Store undiluted at -20°C.

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Description

  • Paxillin, a focal adhesion protein, is a substrate for several tyrosine kinases such as src, FAK, and p120BRC/ABL
  • The tyrosine phosphorylation of paxillin is affected by conditions that change cell-cell adhesion
  • This is consisent with the possibility that paxillin is involved in the regulation of cell morphology
  • Additionally, because of its SH3 binding domain, paxillin associates tightly with FAK and Crk in an extracellular matrix-independent manner
  • Paxillin was initially detected in fibroblasts, and its phosphorylation may be important during neurite extension during differentiation
  • This antibody is routinely tested by western blot analysis
  • Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.