BDB740010
CD2 Rat anti-Mouse, Brilliant Violet 421, Clone: RM2-5, BD Optibuild™
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB740010-Each-of-1 | In Stock | ₹ 35,600.00 |
BDB740010 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 35,600.00
GST (18%): ₹ 6,408.00
Total Price: ₹ 42,008.00
Antigen
CD2
Classification
Monoclonal
Concentration
0.2mg/mL
Description
LFA-2; LFA-3 receptor; Ly37; Ly-37; Lymphocyte antigen 37; T11
Host Species
Rat
Purification Method
Affinity Purified
Regulatory Status
RUO
Target Species
Mouse
Isotype
IgG2b λ
Applications
Flow Cytometry
Clone
RM2-5
Conjugate
Brilliant Violet 421
Formulation
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen
Mouse BALB/c Thymocytes
Quantity
50 μg
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Related Products
Description
- The RM2-5 monoclonal antibody specifically binds to the immunoglobulin superfamily adhesion molecule, CD2 (LFA-2)
- CD2 is a type I transmembrane glycoprotein that serves as the the major receptor for CD48 in the mouse
- CD2 is involved in T-cell activation, immunoregulation, and thymocyte maturation
- In the mouse, CD2 is expressed on peripheral T lymphocytes, B lymphocytes, and NK cells, and a subpopulation of intraepithelial T lymphocytes
- CD2 is expressed throughout mouse thymic ontogeny, except for distinct subsets of the CD4-CD8- early thymocytes
- In the mouse bone marrow, CD2 is expressed on B220+ sIg+ CD43- pre-B cells, but not on CD43+ pro-B cells
- The RM2-5 antibody is one of a set of five anti-mouse CD2 monoclonal antibodies that were classified into two groups according to their mutual competition in binding to cell surface CD2 and which block CD2-mediated cell-cell adhesion
- The antibody was conjugated to BD Horizon™ BV421 which is part of the BD Horizon Brilliant™ Violet family of dyes
- With an Ex Max of 407-nm and Em Max at 421-nm, BD Horizon BV421 can be excited by the violet laser and detected in the standard Pacific Blue™ filter set (eg, 450/50-nm filter)
- BD Horizon BV421 conjugates are very bright, often exhibiting a 10 fold improvement in brightness compared to Pacific Blue conjugates.