BDB740147

CD3 molecular complex Rat anti-Mouse, Brilliant Violet 510, Clone: 17A2, BD Optibuild™

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB740147-Each-of-1 In Stock ₹ 35,600.00

BDB740147 - Each of 1

₹ 35,600.00

In Stock

Quantity

1

Base Price: ₹ 35,600.00

GST (18%): ₹ 6,408.00

Total Price: ₹ 42,008.00

Antigen

CD3 molecular complex

Classification

Monoclonal

Concentration

0.2mg/mL

Description

CD3; CD3 epsilon; Cd3e; CD3ε; T3e

Host Species

Rat

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Mouse

Isotype

IgG2b κ

Applications

Flow Cytometry

Clone

17A2

Conjugate

Brilliant Violet 510

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen

γδ TCR-positive T-T hybridoma D1

Quantity

50 μg

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Description

  • The 17A2 monoclonal antibody specifically binds to the T-cell receptor-associated CD3 complex that is expressed on many thymocytes and mature T lymphocytes
  • Plate-bound 17A2 antibody has been reported to induce IL-2 production by cultured T cells in the absence of accessory cells
  • The binding of the 17A2 antibody to T cells can be blocked by the anti-CD3e mAb 145-2C11 (Cat
  • No
  • 557306/553058/550275)
  • This suggests that the 17A2 antibody recognizes an epitope of the CD3 epsilon chain
  • In vivo treatment with 17A2 antibody has been reported to partially deplete T lymphocytes and temporarily down-modulates CD3 expression on T cells
  • The antibody was conjugated to BD Horizon™ BV510 which is part of the BD Horizon Brilliant™ Violet family of dyes
  • With an Ex Max of 405-nm and Em Max at 510-nm, BD Horizon BV510 can be excited by the violet laser and detected in the BD Horizon V500 (525/50-nm) filter set
  • BD Horizon BV510 conjugates are useful for the detection of dim markers off the violet laser.