BDB740169

CD42b Mouse anti-Human, Brilliant Violet 510, Clone: HIP1, BD Optibuild™

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB740169-Each-of-1 In Stock ₹ 49,306.00

BDB740169 - Each of 1

₹ 49,306.00

In Stock

Quantity

1

Base Price: ₹ 49,306.00

GST (18%): ₹ 8,875.08

Total Price: ₹ 58,181.08

Antigen

CD42b

Classification

Monoclonal

Concentration

0.2mg/mL

Description

GP1BA; GPIbalpha; GP-Ib alpha; GPIb-alpha; CD42b-alpha; Glycocalicin; BSS

Host Species

Mouse

Quantity

50 μg

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications

Flow Cytometry

Clone

HIP1

Conjugate

Brilliant Violet 510

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Human

Isotype

IgG1 κ

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Description

  • The HIP1 monoclonal antibody specifically binds to CD42b
  • CD42b is also known as the Platelet glycoprotein Ib alpha chain that is encoded by the GP1BA gene
  • CD42b is disulfide bonded to CD42c to form a 170 kDa heterodimer, GPIb
  • GPIb forms a noncovalent complex with CD42a and CD42d (CD42 complex) that is expressed on platelets and megakaryocytes
  • The CD42 complex serves as the von Willebrand Factor (vWF) surface receptor involved in the adhesion of platelets to the subendothelium of damaged vascular walls
  • HIP1 inhibits the ristocetin-dependent binding of vWF to platelets and partially inhibits collagen-induced aggregation
  • The antibody was conjugated to BD Horizon™ BV510 which is part of the BD Horizon Brilliant™ Violet family of dyes
  • With an Ex Max of 405-nm and Em Max at 510-nm, BD Horizon BV510 can be excited by the violet laser and detected in the BD Horizon V500 (525/50-nm) filter set
  • BD Horizon BV510 conjugates are useful for the detection of dim markers off the violet laser.