BDB740976
CD42b Mouse anti-Human, Brilliant Violet 786, Clone: HIP1, BD Optibuild™
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB740976-Each-of-1 | In Stock | ₹ 49,306.00 |
BDB740976 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 49,306.00
GST (18%): ₹ 8,875.08
Total Price: ₹ 58,181.08
Antigen
CD42b
Classification
Monoclonal
Concentration
0.2mg/mL
Description
GP1BA; GPIbalpha; GP-Ib alpha; GPIb-alpha; CD42b-alpha; Glycocalicin; BSS
Host Species
Mouse
Quantity
50 μg
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications
Flow Cytometry
Clone
HIP1
Conjugate
Brilliant Violet 786
Formulation
Aqueous buffered solution containing ≤0.09% sodium azide.
Purification Method
Affinity Purified
Regulatory Status
RUO
Target Species
Human
Isotype
IgG1 κ
Related Products
Description
- The HIP1 monoclonal antibody specifically binds to CD42b
- CD42b is also known as the Platelet glycoprotein Ib alpha chain that is encoded by the GP1BA gene
- CD42b is disulfide bonded to CD42c to form a 170 kDa heterodimer, GPIb
- GPIb forms a noncovalent complex with CD42a and CD42d (CD42 complex) that is expressed on platelets and megakaryocytes
- The CD42 complex serves as the von Willebrand Factor (vWF) surface receptor involved in the adhesion of platelets to the subendothelium of damaged vascular walls
- HIP1 inhibits the ristocetin-dependent binding of vWF to platelets and partially inhibits collagen-induced aggregation
- The antibody was conjugated to BD Horizon™ BV786 which is part of the BD Horizon Brilliant™ Violet family of dyes
- This dye is a tandem fluorochrome of BD Horizon BV421 with an Ex Max of 405-nm and an acceptor dye with an Em Max at 786-nm
- BD Horizon BV786 can be excited by the violet laser and detected in a filter used to detect Cy™7-like dyes (eg, 780/60-nm filter).