BDB740675
CD106 Rat anti-Mouse, Brilliant Violet 711, Clone: 429 (MVCAM.A), BD Optibuild™
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB740675-Each-of-1 | In Stock | ₹ 35,600.00 |
BDB740675 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 35,600.00
GST (18%): ₹ 6,408.00
Total Price: ₹ 42,008.00
Antigen
CD106
Classification
Monoclonal
Concentration
0.2mg/mL
Description
Vcam-1; Vascular cell adhesion molecule 1; Vascular cell adhesion protein 1
Host Species
Rat
Purification Method
Affinity Purified
Regulatory Status
RUO
Target Species
Mouse
Isotype
IgG2a κ
Applications
Flow Cytometry
Clone
429 (MVCAM.A)
Conjugate
Brilliant Violet 711
Formulation
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen
Mouse preadipose cell line PA6
Quantity
50 μg
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
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Description
- The 429 monoclonal antibody specifically binds to both the long (∽110 kDa) transmembrane-spanning form and the truncated (∽47 kDa) GPI-linked form of vascular cell adhesion molecule-1 (VCAM-1, CD106)
- CD106 is constitutively expressed on bone marrow stromal cells, myeloid cells, and splenic dendritic cells
- Its expression on endothelial cells is upregulated by inflammatory cytokines and in certain pathologic conditions
- CD106 expression has also been detected on apoptotic thymocytes, splenocytes, and lymphoid cell lines
- VCAM-1 is a counter-receptor for VLA-4 ( α 4β 1 integrin) and LPAM-1 ( α 4β 7 integrin), and the 429 antibody partially blocks VCAM-1-mediated binding functions
- Source of the immunogen was the mouse preadipose cell line PA6.