ENM501

GM-CSF Monoclonal Antibody (1089), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 ENM501-Each-of-1 In Stock ₹ 42,319.50

ENM501 - Each of 1

₹ 42,319.50

In Stock

Quantity

1

Base Price: ₹ 42,319.50

GST (18%): ₹ 7,617.51

Total Price: ₹ 49,937.01

Antigen

GM-CSF

Classification

Monoclonal

Concentration

1.0 mg/mL

Formulation

PBS with no preservative

Gene Accession No.

P04141

Gene Symbols

CSF2

Immunogen

Glycosylated, CHO-derived recombinant human GM-CSF

Quantity

500 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1 κ

Applications

ELISA

Clone

1089

Conjugate

Unconjugated

Gene

CSF2

Gene Alias

colony stimulating factor 2; colony stimulating factor 2 (granulocyte-macrophage); colony-stimulating factor; CSF; CSF2; Csfgm; cytokine; GMCSF; Gm-CSf; granulocyte macrophage colony stimulating factor; granulocyte macrophage-colony stimulating factor; granulocyte-macrophage colony stimulating factor 2; granulocyte-macrophage colony-stimulating factor; MGC131935; MGC138897; MGC151255; MGC151257; MGI-IGM; M-GM-CSF; molgramostin; put. GM-CSF; sargramostim

Host Species

Mouse

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

1437

Content And Storage

-20°C

Form

Liquid

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Description

  • M501 targets Human GM-CSF in ELISA applications and shows reactivity with Human samples
  • The M501 immunogen is glycosylated, CHO-derived recombinant human GM-CSF
  • M501 detects Human GM-CSF which has a predicted molecular weight of approximately 14 kDa
  • This product has been tested for endotoxins by limulus amoebocyte lysate (LAL) assay and contains an endotoxin concentration of less than or equal to 10 endotoxin units per milligram (EU/mg)
  • The GM-CSF gene encodes for a cytokine that regulates the production, differentiation, and function of macrophages and granulocytes
  • The active form of the protein exists as a homodimer in the extracellular space
  • This gene is located in a cluster of related genes at the chromosome region 5q31, which has been associated with interstitial deletions in the 5q- syndrome and acute myelogenous leukemia
  • Other genes in the cluster include interleukins 4, 5, and 13
  • The gene is involved in promoting tissue inflammation
  • Elevated levels of cytokines, including the one produced by this gene, have been observed in SARS-CoV-2 infected patients with acute respiratory distress syndrome
  • Mice that lack this gene or its receptor have been shown to develop pulmonary alveolar proteinosis.