GM-CSF Monoclonal Antibody (31G6), Biotin, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | ENMM500DB-Each-of-1 | In Stock | ₹ 45,968.50 |
ENMM500DB - Each of 1
In Stock
Quantity
1
Base Price: ₹ 45,968.50
GST (18%): ₹ 8,274.33
Total Price: ₹ 54,242.83
Antigen
GM-CSF
Classification
Monoclonal
Concentration
0.5 mg/mL
Formulation
PBS with 4% BSA and proprietary Preservative
Gene Accession No.
P01587
Gene Symbols
CSF2
Immunogen
Recombinant mouse GM-CSF
Quantity
250 μg
Primary or Secondary
Primary
Target Species
Mouse
Product Type
Antibody
Isotype
IgG1
Applications
Western Blot
Clone
31G6
Conjugate
Biotin
Gene
CSF2
Gene Alias
colony stimulating factor 2; colony stimulating factor 2 (granulocyte-macrophage); colony-stimulating factor; CSF; CSF2; Csfgm; cytokine; GMCSF; Gm-CSf; granulocyte macrophage colony stimulating factor; granulocyte macrophage-colony stimulating factor; granulocyte-macrophage colony stimulating factor 2; granulocyte-macrophage colony-stimulating factor; MGC131935; MGC138897; MGC151255; MGC151257; MGI-IGM; M-GM-CSF; molgramostin; put. GM-CSF; sargramostim
Host Species
Rat
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
12981
Content And Storage
-20°C
Form
Liquid
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Description
- MM500DB targets Mouse GM-CSF in WB applications and shows reactivity with mouse samples
- The MM500DB immunogen is recombinant mouse GM-CSF
- MM500DB detects Mouse GM-CSF which has a predicted molecular weight of approximately 14 kDa
- The MM500DB mouse GMCSF antibody (biotinylated conjugate of clone 31G6) has successfully been paired as the detection antibody in a sandwich ELISA with capture antibody MM500C (clone 22E9) Typical dilutions for sandwich ELISA include 1 μg/mL for coating and 0.125 - 0.25 μg/mL for detection
- Biotinylated antibody MM500DB (clone 31G6) and antibody MM500C (clone 22E9) have successfully been used in combination with recombinant mouse GMCSF protein SMGMCSF in ELISA applications
- This antibody is produced by injecting Rat IgG secreting hybridoma cells into the peritoneum of mice
- The resulting ascites is collected from the mice and the antibody is purified
- The GM-CSF gene encodes for a cytokine that regulates the production, differentiation, and function of macrophages and granulocytes
- The active form of the protein exists as a homodimer in the extracellular space
- This gene is located in a cluster of related genes at the chromosome region 5q31, which has been associated with interstitial deletions in the 5q- syndrome and acute myelogenous leukemia
- Other genes in the cluster include interleukins 4, 5, and 13
- The gene is involved in promoting tissue inflammation
- Elevated levels of cytokines, including the one produced by this gene, have been observed in SARS-CoV-2 infected patients with acute respiratory distress syndrome
- Mice that lack this gene or its receptor have been shown to develop pulmonary alveolar proteinosis.