CD31 Monoclonal Antibody (HEC7), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | ENMA3100-Each-of-1 | In Stock | ₹ 44,633.50 |
ENMA3100 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,633.50
GST (18%): ₹ 8,034.03
Total Price: ₹ 52,667.53
Antigen
CD31
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with no preservative
Gene Accession No.
P16284, P51866
Gene Symbols
Pecam1
Immunogen
Human PECAM-1
Quantity
200 μg
Primary or Secondary
Primary
Target Species
Bovine, Human
Product Type
Antibody
Isotype
IgG2a
Applications
Flow Cytometry, Immunocytochemistry, Western Blot
Clone
HEC7
Conjugate
Unconjugated
Gene
Pecam1
Gene Alias
C85791; CD31; CD31 antigen; CD31, PECAM-1; CD31/EndoCAM; endoCAM; GPIIA'; I79_008304; PECA1; Pecam; PECAM1; Pecam-1; platelet and endothelial cell adhesion molecule 1; platelet endothelial cell adhesion molecule; platelet endothelial cell adhesion molecule-1; platelet/endothelial cell adhesion molecule (CD31 antigen); platelet/endothelial cell adhesion molecule 1; type I transmembrane endothelial adhesion molecule
Host Species
Mouse
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
282303, 5175
Content And Storage
-20°C
Form
Liquid
Related Products
Description
- MA3100 targets CD31 in ICC/IF and ACS applications and shows reactivity with Human and Bovine samples
- The MA3100 immunogen is human PECAM-1
- MA3100 detects CD31 which has a predicted molecular weight of approximately 80 kDa
- This product has been tested for endotoxins by limulus amoebocyte lysate (LAL) assay and contains an endotoxin concentration of less than or equal to 10 endotoxin units per milligram (EU/mg)
- CD31 (platelet endothelial cell adhesion molecule-1, PECAM-1) is an inhibitory coreceptor involved in regulation of T cell and B cell signaling by a dual immunoreceptor tyrosine-based inhibitory motif (ITIM) that upon associated kinases-mediated phosphorylation provide docking sites for protein-tyrosine phosphatases
- CD31 is expressed ubiquitously within the vascular compartment and is located mainly at junctions between adjacent cells
- N-terminal Ig-like domain of CD31 is responsible for its homophilic binding, which plays an important role in cell-cell interactions
- CD31 is a multifunctional molecule with diverse roles in modulation of integrin-mediated cell adhesion, transendothelial migration, angiogenesis, apoptosis, negative regulation of immunoreceptor signaling, autoimmunity, macrophage phagocytosis, IgE-mediated anaphylaxis and thrombosis
- It is one of key regulatory molecules in vascular system.