CD56 Recombinant Mouse Monoclonal Antibody (PDH0-07), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | FEMA550656-Each-of-1 | In Stock | ₹ 42,275.00 |
FEMA550656 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 42,275.00
GST (18%): ₹ 7,609.50
Total Price: ₹ 49,884.50
Antigen
CD56
Classification
Recombinant Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 0.1% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.
P13591
Gene Symbols
Ncam1
Immunogen
Synthetic peptide aa 800-858/858.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Form
Liquid
Applications
Immunohistochemistry (Paraffin)
Clone
PDH0-07
Conjugate
Unconjugated
Gene
Ncam1
Gene Alias
adhesion molecule, antigen recognized by monoclonal antibody 5.1H11, Cd56, CD-56, CD56 120 kDa GPI-linked isoform, CD56 140 kDa isoform, CD56 140 kDa VASE isoform, E NCAM, E-NCAM, MSK39, N CAM1, NCAM, N-CAM, Ncam1, N-CAM-1, NCAM-1, NCAMC, NCAM-C, neural cell adhesion molecule, Neural cell adhesion molecule 1, neural cell adhesion molecule, NCAM, sCD56, sNCAM, soluble CD56, soluble NCAM
Host Species
Mouse
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
4684
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype
IgG1
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Description
- Positive control: Human appendix tissue, human glioma tissue, human brain tissue, human smooth muscle tissue
- Predicted band size: 95 kDa Subcellular Location: Cell membrane, Secreted
- CD56 (NCAM, neural cell adhesion molecule) is a transmembrane glycoprotein of the immunoglobulin family that serves as an adhesive molecule and is ubiquitously expressed in the nervous system in isoforms ranging from 120-180 kDa
- CD56 is found on T cells and NK cells, and is involved in cell migration, axonal growth, pathfinding and synaptic plasticity
- Polysialic modification results in reduction of CD56-mediated cell adhesion
- Through its extracellular region, CD56 mediates homophilic and heterophilic interactions by binding extracellular matrix components such as laminin and integrins
- CD56 is expressed on most neuroectodermal derived cell lines, tissues and neoplasms such as retinoblastoma, medulloblastoma, astrocytomas and neuroblastoma
- Further, CD56 is a widely used neuroendocrine marker with a high sensitivity for neuroendocrine tumors and ovarian granulosa cell tumors
- Diseases associated with CD56 dysfunction include rabies and blastic plasmacytoid dendritic cell neoplasms.