IL-2 Monoclonal Antibody (5H4), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | ENMM101-Each-of-1 | In Stock | ₹ 44,455.50 |
ENMM101 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,455.50
GST (18%): ₹ 8,001.99
Total Price: ₹ 52,457.49
Antigen
IL-2
Classification
Monoclonal
Concentration
1.0 mg/mL
Formulation
PBS with no preservative
Gene Accession No.
P04351
Gene Symbols
IL2
Immunogen
Recombinant mouse IL-2
Quantity
500 μg
Primary or Secondary
Primary
Target Species
Mouse
Product Type
Antibody
Isotype
IgG2b
Applications
ELISA, Western Blot
Clone
5H4
Conjugate
Unconjugated
Gene
IL2
Gene Alias
aldesleukin; cytokine; H-IL-2; il 2; Il2; Il-2; ILN; Interleukin; interleukin 2; interleukin 2 precursor; interleukin 2 variant IL2delta2; Interleukin2; Interleukin-2; interleukin-2 precursor; interleukin-2 precursor protein; interleukin-2; interleukin 2; Involved in regulation of T cell clonal expansion; involved in regulation of T-cell clonal expansion; lymphokine; M-IL-2; patial sequence of Interleukin-2; POIL2; porcine Interleukin 2; T cell growth factor; T-cell growth factor; T-cell growth factor (TCGF); TCGF
Host Species
Rat
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
16183
Content And Storage
-20°C
Form
Liquid
Related Products
Description
- MM101 targets IL-2 in ELISA, and WB applications and shows reactivity with mouse samples
- The MM101 immunogen is recombinant mouse IL-2
- MM101 detects IL-2 which has a predicted molecular weight of approximately 17 kDa
- The MM101 mouse IL2 antibody (clone 5H4) has successfully been paired as the coating antibody in a sandwich ELISA with detection antibody MM102B (biotinylated conjugate of clone 1A12)
- Typical dilutions for sandwich ELISA include 1 μg/mL for coating and 0.125 - 0.25 μg/mL for detection
- Antibody MM101 (clone 5H4) and biotinylated antibody MM102B (clone 1A12) have successfully been used in combination with recombinant mouse IL2 protein SMIL2 in ELISA applications
- This antibody is produced by injecting Rat IgG secreting hybridoma cells into the peritoneum of mice
- The resulting ascites is collected from the mice and the antibody is purified
- This product has been tested for endotoxins by limulus amoebocyte lysate (LAL) assay and contains an endotoxin concentration of less than or equal to 10 endotoxin units per milligram (EU/mg)
- Interleukin 2 (IL-2) is an immuno-modulatory cytokine that is important for the proliferation of activated T cells, differentiation of B cells, natural killer cells, monocytes and macrophages
- IL-2 signals through the IL-2 receptor (IL-2R), a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL-4) and interleukin 7 (IL-7)
- The expression of the IL-2 gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene
- The targeted disruption of a gene similar to IL-2 in mice leads to an μgcerative colitis-like disease that suggests an essential role of this gene in the immune response to antigenic stimuli.