IL-6 Monoclonal Antibody (32C11), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | ENMM600D-Each-of-1 | In Stock | ₹ 46,502.50 |
ENMM600D - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
IL-6
Classification
Monoclonal
Concentration
1.0 mg/mL
Formulation
PBS with no preservative
Gene Accession No.
P08505
Gene Symbols
Il6
Immunogen
Recombinant mouse IL-6
Quantity
500 μg
Primary or Secondary
Primary
Target Species
Mouse
Product Type
Antibody
Isotype
IgG2a
Applications
ELISA, Western Blot
Clone
32C11
Conjugate
Unconjugated
Gene
Il6
Gene Alias
B-cell differentiation factor; B-cell hybridoma growth factor; B-cell stimulatory factor 2; BSF2; BSF-2; CDF; CHIL-6; CTL differentiation factor; cytokine; HGF; H-IL-6; HSF; hybridoma growth factor; Ifnb2; IFN-beta-2; Il6; IL-6; ILg6; ILN; interferon beta-2; Interleukin; interleukin 6; Interleukin 6 (interferon, beta 2); interleukin 6 precursor; interleukin BSF-2; interleukin HP-1; Interleukin6; Interleukin-6; interleukin-6 precursor; interleukin-6 protein; M-IL-6; prointerleukin 6; R-IL-6
Host Species
Rat
Purification Method
Ammonium sulfate precipitation
Regulatory Status
RUO
Gene ID (Entrez)
16193
Content And Storage
-20°C
Form
Liquid
Related Products
Description
- MM600D targets IL-6 in ELISA, and WB applications and shows reactivity with mouse samples
- The MM600D immunogen is recombinant mouse IL-6
- MM600D detects IL-6 which has a predicted molecular weight of approximately 22 kDa
- The MM600D mouse IL6 antibody (clone 32C11) has successfully been paired as the coating antibody in a sandwich ELISA with detection antibody MM600CB (biotinylated conjugate of clone 20F3)
- Typical dilutions for sandwich ELISA include 1 μg/mL for coating and 0.125 - 0.25 μg/mL for detection
- Antibody MM600D (clone 32C11) and biotinylated antibody MM600CB (clone 20F3) have successfully been used in combination with recombinant mouse IL6 protein SMIL6 in ELISA applications
- This antibody is produced by injecting Rat IgG secreting hybridoma cells into the peritoneum of mice
- The resulting ascites is collected from the mice and the antibody is purified
- This product has been tested for endotoxins by limulus amoebocyte lysate (LAL) assay and contains an endotoxin concentration of less than or equal to 10 endotoxin units per milligram (EU/mg)
- IL-6 is a gene that encodes a cytokine that plays a role in inflammation and the maturation of B cells
- The protein produced by this gene is an endogenous pyrogen that can induce fever in people with autoimmune diseases or infections
- The gene is primarily expressed at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha
- The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis
- Elevated levels of the encoded protein have been found in virus infections, including COVID-19 (disease caused by SARS-CoV-2)
- Diseases associated with IL6 include Kaposi Sarcoma and Rheumatoid Arthritis, Systemic Juvenile.