IL-5 Monoclonal Antibody (TRFK4), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | ENMM550D-Each-of-1 | In Stock | ₹ 46,502.50 |
ENMM550D - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
IL-5
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with no preservative
Gene Accession No.
P04401
Gene Symbols
Il5
Immunogen
Recombinant mouse IL-5
Quantity
500 μg
Primary or Secondary
Primary
Target Species
Mouse
Product Type
Antibody
Isotype
IgG2a
Applications
ELISA, Inhibition Assays, Western Blot
Clone
TRFK4
Conjugate
Unconjugated
Gene
Il5
Gene Alias
B-cell differentiation factor I; B-cell growth factor II; BCGF-II; colony-stimulating factor, eosinophil; cytotoxic T-lymphocyte inducer; EDF; Eosinophil differentiation factor; IL5; IL-5; ILN; Interleukin; Interleukin 5; Interleukin 5 (colony-stimulating factor eosinophil); Interleukin 5 (colony-stimulating factor, eosinophil); Interleukin5; interleukin-5; T-cell replacing factor; TRF
Host Species
Rat
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
16191
Content And Storage
-20°C
Form
Liquid
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Description
- MM550D targets IL-5 in ELISA, IA, and WB applications and shows reactivity with mouse samples
- The MM550D immunogen is recombinant mouse IL-5
- MM550D detects IL-5 which has a predicted molecular weight of approximately 13 kDa
- The MM550D mouse IL5 antibody (clone TRFK4) has successfully been paired as the coating antibody in a sandwich ELISA with detection antibody MM550CB (biotinylated conjugate of clone TRFK5)
- Typical dilutions for sandwich ELISA include 1 μg/mL for coating and 0.125 - 0.25 μg/mL for detection
- Antibody MM550D (clone TRFK4) and biotinylated antibody MM550CB (clone TRFK5) have successfully been used in combination with recombinant mouse IL5 protein SMIL5 in ELISA applications
- This antibody is produced by injecting Rat IgG secreting hybridoma cells into the peritoneum of mice
- The resulting ascites is collected from the mice and the antibody is purified
- This product is a Low Endotoxin formulation
- This product has been tested for endotoxins by limulus amoebocyte lysate (LAL) assay and contains an endotoxin concentration of less than or equal to 10 endotoxin units per milligram (EU/mg)
- IL-5 is a cytokine that acts as a growth and differentiation factor for both B cells and eosinophils
- IL-5 cytokine is a main regulator of eosinopoiesis, eosinophil maturation and activation
- The elevated production of this cytokine is reported to be related to asthma or hypereosinophilic syndromes
- The receptor of IL-5 cytokine is a heterodimer, whose beta subunit is shared with the receptors for interleukine 3 (IL3) and colony stimulating factor 2 (CSF2/GM-CSF)
- IL-5, together with those for interleukin 4 (IL4), interleukin 13 (IL13), and CSF2, form a cytokine gene cluster on chromosome 5
- IL-5, IL4, and IL13 are found to be regulated coordinately by long-range regulatory elements spread over 120 kilobases on chromosome 5q31.