FEMA549784

Phospho-Rb (Ser780) Recombinant Rabbit Monoclonal Antibody (2E9), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 FEMA549784-Each-of-1 In Stock ₹ 37,202.00

FEMA549784 - Each of 1

₹ 37,202.00

In Stock

Quantity

1

Base Price: ₹ 37,202.00

GST (18%): ₹ 6,696.36

Total Price: ₹ 43,898.36

Antigen

Phospho-Rb (Ser780)

Classification

Recombinant Monoclonal

Concentration

0.53 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.

P06400

Gene Symbols

RB1

Immunogen

A synthesized peptide derived from human Phospho-RB1 (S780)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

Applications

ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation

Clone

2E9

Conjugate

Unconjugated

Gene

RB1

Gene Alias

Cleaved Rb, delta RB-p70, DRb-p70, exon 17 tumor GOS561 substitution mutation causes premature stop, GOS563 exon 17 substitution mutation causes premature stop, OSRC, p104, p104 chicken Rb, P105RB, p105-Rb, Phospho-Retinoblastoma, pp105, pp110, PPP1R130, pRb, prepro-retinoblastoma-associated protein, protein phosphatase 1, regulatory subunit 130, rb, RB transcriptional corepressor 1, RB1, Rb-1, Rb-p70, Retin, Retinoblastoma, retinoblastoma 1, retinoblastoma 1 (including osteosarcoma), retinoblastoma 1 protein, retinoblastoma gene, retinoblastoma isoform A, retinoblastoma protein, retinoblastoma suspectibility protein, retinoblastoma tumor suppressor, retinoblastoma-associated protein

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

5925

Content And Storage

-20°C or -80°C if preferred

Isotype

IgG

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Description

  • Rb is a tumor suppressor nuclear phosphoprotein capable of binding to DNA
  • It is phosphorylated on serine and threonine, but not on tyrosine residues
  • It forms a complex with SV40 large T antigen, adenovirus E1A, and human papilloma virus-16 E
  • Rb protein may act by regulating transcription and loss of its function leads to uncontrolled cell growth
  • Aberrations in the RB gene have been implicated in cancers of breast, colon, prostate, kidney, nasopharynx, and leukemia.