Rb Recombinant Rabbit Monoclonal Antibody (HL2465), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | FEMA550542-Each-of-1 | In Stock | ₹ 41,385.00 |
FEMA550542 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 41,385.00
GST (18%): ₹ 7,449.30
Total Price: ₹ 48,834.30
Antigen
Rb
Classification
Recombinant Monoclonal
Concentration
1 mg/mL
Formulation
PBS with no preservative
Gene Accession No.
P06400
Gene Symbols
RB1
Immunogen
Recombinant fragment of human Rb.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Form
Liquid
Applications
Western Blot
Clone
HL2465
Conjugate
Unconjugated
Gene
RB1
Gene Alias
Cleaved Rb, delta RB-p70, DRb-p70, exon 17 tumor GOS561 substitution mutation causes premature stop, GOS563 exon 17 substitution mutation causes premature stop, OSRC, p104, p104 chicken Rb, P105RB, p105-Rb, Phospho-Retinoblastoma, pp105, pp110, PPP1R130, pRb, prepro-retinoblastoma-associated protein, protein phosphatase 1, regulatory subunit 130, rb, RB transcriptional corepressor 1, RB1, Rb-1, Rb-p70, Retin, Retinoblastoma, retinoblastoma 1, retinoblastoma 1 (including osteosarcoma), retinoblastoma 1 protein, retinoblastoma gene, retinoblastoma isoform A, retinoblastoma protein, retinoblastoma suspectibility protein, retinoblastoma tumor suppressor, retinoblastoma-associated protein
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
5925
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype
IgG
Related Products
Description
- Rb is a tumor suppressor nuclear phosphoprotein capable of binding to DNA
- It is phosphorylated on serine and threonine, but not on tyrosine residues
- It forms a complex with SV40 large T antigen, adenovirus E1A, and human papilloma virus-16 E
- Rb protein may act by regulating transcription and loss of its function leads to uncontrolled cell growth
- Aberrations in the RB gene have been implicated in cancers of breast, colon, prostate, kidney, nasopharynx, and leukemia.