PTBP1 Recombinant Rabbit Monoclonal Antibody (8A1), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | FEMA549892-Each-of-1 | In Stock | ₹ 37,202.00 |
FEMA549892 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 37,202.00
GST (18%): ₹ 6,696.36
Total Price: ₹ 43,898.36
Antigen
PTBP1
Classification
Recombinant Monoclonal
Concentration
0.22 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4
Gene Accession No.
P26599
Gene Symbols
PTBP1
Immunogen
A synthesized peptide derived from human PTBP1
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Form
Liquid
Applications
ELISA, Immunohistochemistry (Paraffin), Western Blot
Clone
8A1
Conjugate
Unconjugated
Gene
PTBP1
Gene Alias
57 kDa RNA-binding protein PPTB-1, AA407203, AL033359, Heterogeneous nuclear ribonucleoprotein I, heterogeneous nuclear ribonucleoprotein polypeptide I, hnRNP I, HNRNPI, HNRNP-I, HNRPI, MGC10830, MGC8461, polypyrimidine tract binding protein (heterogeneous nuclear ribonucleoprotein I), polypyrimidine tract binding protein 1, polypyrimidine tract-binding protein, polypyrimidine tract-binding protein 1, polypyrimidine-tract binding protein, pPTB, PTB, PTB-1, PTB2, PTB3, PTB4, PTBP1, PTB-T, Pybp, Pybp1, Pybp2, pyrimidine binding protein 1, pyrimidine binding protein 2, RNA-binding protein
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
5725
Content And Storage
-20°C or -80°C if preferred
Isotype
IgG
Related Products
Description
- This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs)
- The hnRNPs are RNA-binding proteins and they complex with heterogeneous nuclear RNA (hnRNA)
- These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport
- While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm
- The hnRNP proteins have distinct nucleic acid binding properties
- The protein encoded by this gene has four repeats of quasi-RNA recognition motif (RRM) domains that bind RNAs
- This protein binds to the intronic polypyrimidine tracts that requires pre-mRNA splicing and acts via the protein degradation ubiquitin-proteasome pathway
- It may also promote the binding of U2 snRNP to pre-mRNAs
- This protein is localized in the nucleoplasm and it is also detected in the perinucleolar structure
- Alternatively spliced transcript variants encoding different isoforms have been described.