PCBP2 Recombinant Rabbit Monoclonal Antibody (JE65-05), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | FEMA550663-Each-of-1 | In Stock | ₹ 42,275.00 |
FEMA550663 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 42,275.00
GST (18%): ₹ 7,609.50
Total Price: ₹ 49,884.50
Antigen
PCBP2
Classification
Recombinant Monoclonal
Concentration
1 mg/mL
Formulation
TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.
Q15366, Q61990
Gene Symbols
PCBP2
Immunogen
Synthetic peptide within human PCBP2 aa 251-300/365.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Clone
JE65-05
Conjugate
Unconjugated
Gene
PCBP2
Gene Alias
Alpha CP2, Alpha-CP2, alphaCP-2, AW412548, CBP, CTBP, fb36h02, Heterogeneous nuclear ribonucleoprotein E2, heterogeneous nuclear ribonucleoprotein X, heterogenous nuclear ribonucleoprotein E2, hnRNP E2, hnRNP X, HNRNPE2, hnRNP-E2, Hnrnpx, HNRPE2, Hnrpx, MGC110998, Pcbp2, pcbp2 protein, PCBP3, poly(rC) binding protein 2, poly(rC)-binding protein 2, Putative heterogeneous nuclear ribonucleoprotein X, rCbinding protein 2, wu:fb36h02, zgc:55964
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
18521, 5094
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype
IgG
Related Products
Description
- Positive control: Jurkat cell lysate, Hela cell lysate, 293 cell lysate, RAW264.7 cell lysate, human kidney tissue, mouse brain tissue
- Predicted band size: 39 kDa Subcellular Location: Cytoplasm, Nucleus
- The protein encoded by this gene appears to be multifunctional
- Along with PCBP-1 and hnRNPK, it is one of the major cellular poly(rC)-binding proteins
- The encoded protein contains three K-homologous (KH) domains which may be involved in RNA binding
- Together with PCBP-1, this protein also functions as a translational coactivator of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES, promoting poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure
- It has also been implicated in translational control of the 15-lipoxygenase mRNA, human papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA
- The encoded protein is also suggested to play a part in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mRNA stability
- This multiexon structural mRNA is thought to be retrotransposed to generate PCBP-1, an intronless gene with functions similar to that of PCBP2
- This gene and PCBP-1 have paralogous genes (PCBP3 and PCBP4) which are thought to have arisen as a result of duplication events of entire genes
- This gene also has two processed pseudogenes (PCBP2P1 and PCBP2P2)
- Multiple transcript variants encoding different isoforms have been found for this gene.