FEMA549894

GDF15 Recombinant Rabbit Monoclonal Antibody (8E5), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 FEMA549894-Each-of-1 In Stock ₹ 37,202.00

FEMA549894 - Each of 1

₹ 37,202.00

In Stock

Quantity

1

Base Price: ₹ 37,202.00

GST (18%): ₹ 6,696.36

Total Price: ₹ 43,898.36

Antigen

GDF15

Classification

Recombinant Monoclonal

Concentration

0.9 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.

Q99988

Gene Symbols

Gdf15

Immunogen

A synthesized peptide derived from human GDF15

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

Applications

ELISA, Immunohistochemistry (Paraffin)

Clone

8E5

Conjugate

Unconjugated

Gene

Gdf15

Gene Alias

Gdf15, GDF-15, growth differentiation factor 15, growth/differentiation factor 15, macrophage inhibiting cytokine-1, macrophage inhibitory cytokine 1, MIC1, MIC-1, NAG1, NAG-1, NRG-1, NSAID (nonsteroidal anti-inflammatory drug)-activated protein 1, NSAID-activated gene 1 protein, NSAID-regulated gene 1 protein, PDF, PLAB, Placental bone morphogenetic protein, placental TGF-beta, Prostate differentiation factor, PTGFB, PTGF-beta, SBF

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

9518

Content And Storage

-20°C or -80°C if preferred

Isotype

IgG

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Description

  • GDF-15 belongs to the TGF-beta cytokine family, whose members play an important role during prenatal development and postnatal growth, and the remodeling and maintenance of a variety of tissues and organs
  • GDF-15 is expressed predominantly in the placenta and, to a much lesser extent, in various other tissues
  • The presence of GDF-15 in amniotic fluid and its elevated levels in the sera of pregnant women suggest GDF-15's involvement in gestation and embryonic development
  • GDF-15 generally exerts tumor suppressive activities and is one of the predominant factors produced and secreted in response to activation of the p53 pathway
  • Interestingly, the serum level of GDF-15 is positively correlated with neoplastic progression of several tumor types, including certain colorectal, pancreatic, and prostate cancers.