FEMA549874

Factor X Recombinant Rabbit Monoclonal Antibody (3F2), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 FEMA549874-Each-of-1 In Stock ₹ 37,202.00

FEMA549874 - Each of 1

₹ 37,202.00

In Stock

Quantity

1

Base Price: ₹ 37,202.00

GST (18%): ₹ 6,696.36

Total Price: ₹ 43,898.36

Antigen

Factor X

Classification

Recombinant Monoclonal

Concentration

0.9 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.

P00742

Gene Symbols

F10

Immunogen

A synthesized peptide derived from human Factor X

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

Applications

ELISA, Immunohistochemistry (Paraffin)

Clone

3F2

Conjugate

Unconjugated

Gene

F10

Gene Alias

Activated factor Xa heavy chain, blood coagulation factor X, Cf10, coagulation factor 10, coagulation factor X, coagulation factor X protein, F10, Factor 10, Factor X heavy chain, Factor X light chain, factor Xa, Factor10, FX, FXA, prothrombinase, RP11-98F14.9, stuart factor, Stuart-Prower factor, Unknown (protein for IMAGE:8121240), unnamed protein product

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

2159

Content And Storage

-20°C or -80°C if preferred

Isotype

IgG

Related Products

Img

Thermo Scientific

FEMA550689

--

Img

Thermo Scientific

FEMA549894

--

Img

Thermo Scientific

FEMA550016

--

Img

Thermo Scientific

FEMA549861

--

Img

Thermo Scientific

FEMA549800

--

Img

Thermo Scientific

FEMA549793

--

Img

Thermo Scientific

FEMA549939

--

Img

Thermo Scientific

FEMA549822

--

Description

  • F10 undergoes multiple processing steps before its preproprotein is converted to a mature two-chain form by the excision of the tripeptide RKR
  • Two chains of the factor are held together by 1 or more disulfide bonds; the light chain contains 2 EGF-like domains, while the heavy chain contains the catalytic domain which is structurally homologous to those of the other hemostatic serine proteases
  • The mature factor is activated by the cleavage of the activation peptide by factor IXa (in the intrisic pathway), or by factor VIIa (in the extrinsic pathway)
  • The activated factor then converts prothrombin to thrombin in the presence of factor Va, Ca+2, and phospholipid during blood clotting
  • Mutations of this gene result in factor X deficiency, a hemorrhagic condition of variable severity.