FEMA549937

TACC3 Recombinant Rabbit Monoclonal Antibody (10G7), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 FEMA549937-Each-of-1 In Stock ₹ 37,202.00

FEMA549937 - Each of 1

₹ 37,202.00

In Stock

Quantity

1

Base Price: ₹ 37,202.00

GST (18%): ₹ 6,696.36

Total Price: ₹ 43,898.36

Antigen

TACC3

Classification

Recombinant Monoclonal

Concentration

1.15 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.

Q9Y6A5

Gene Symbols

TACC3

Immunogen

A synthesized peptide derived from human TACC3

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

Applications

ELISA, Immunohistochemistry (Paraffin), Western Blot

Clone

10G7

Conjugate

Unconjugated

Gene

TACC3

Gene Alias

Aint, Arnt interacting protein, ARNT-interacting protein, C86661, ERIC1, ERIC-1, Tacc3, transforming acidic coiled coil 3, transforming acidic coiled-coil containing protein 3, transforming acidic coiled-coil-containing protein 3, transforming, acidic coiled-coil containing protein 3

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

10460

Content And Storage

-20°C or -80°C if preferred

Isotype

IgG

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Description

  • TACC1 is located on 8p11 chromosomal region that is amplified in approximately 15% of all breast tumor samples
  • The short arm of chromosome 8 also contains FGFR1 whose expression is enhanced in most breast cancer tumors
  • TACC family members, TACC1, TACC2, and TACC3, map very closely to the corresponding FGFR1, FGFR2, FGFR3 genes on chromosomes 4,8, and 10
  • Subsequently, since they are phylogenetically related, it is proposed that TACC and FGFR have similar roles in cell growth and differentiation
  • Also, TACC1 contains a conserved C-terminal region as in the Drosophila homolog, D-TACC
  • It has been shown that D-TACC is necessary for normal spindle function, and the mammalian TACC proteins appears to interact with centrosomes and microtubules in a similar manner.