FEMA549945

RNF20 Recombinant Rabbit Monoclonal Antibody (2H12), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 FEMA549945-Each-of-1 In Stock ₹ 37,202.00

FEMA549945 - Each of 1

₹ 37,202.00

In Stock

Quantity

1

Base Price: ₹ 37,202.00

GST (18%): ₹ 6,696.36

Total Price: ₹ 43,898.36

Antigen

RNF20

Classification

Recombinant Monoclonal

Concentration

1.5 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.

Q5VTR2

Gene Symbols

RNF20

Immunogen

A synthesized peptide derived from human RNF20

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

Applications

ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone

2H12

Conjugate

Unconjugated

Gene

RNF20

Gene Alias

4833430L21Rik, AW540162, BRE1, BRE1 E3 ubiquitin ligase homolog, BRE1A, BRE1-A, C79397, E3 ubiquitin-protein ligase BRE1A, FLJ11189, FLJ20382, hBRE1, HNF3B, homolog of S. cerevisiae BRE1, hypothetical protein, KIAA2779, Kiaa4116, MGC129667, MGC129668, mKIAA4116, RCJMB04_5a23, RING finger protein 20, ring finger protein 20, E3 ubiquitin protein ligase, RING-type E3 ubiquitin transferase BRE1A, Rnf20, TCF3B

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

56254

Content And Storage

-20°C or -80°C if preferred

Isotype

IgG

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Description

  • RNF20 is an E3 ubiquitin ligase that regulates chromosome structure by monoubiquitinating histone H2B
  • RNF20 selectively suppresses the expression of some genes such as several protooncogenes and growth-related genes, including many genes that are induced by epidermal growth factor by interfering with chromatin recruitment of transcription elongation factor SII (TFIIS)
  • In contrast, RNF20 also positively regulates the p53 tumor suppressor as well as numerous histone H2A and H2B genes
  • Together with the deubiquitinase USP44, RNF20 regulates stem cell differentiation by modulating H2B monoubiquitination.