FEMA549983

CD100 Recombinant Human Monoclonal Antibody (5D12), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 FEMA549983-Each-of-1 In Stock ₹ 37,202.00

FEMA549983 - Each of 1

₹ 37,202.00

In Stock

Quantity

1

Base Price: ₹ 37,202.00

GST (18%): ₹ 6,696.36

Total Price: ₹ 43,898.36

Antigen

CD100

Classification

Recombinant Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.03% Proclin 300, pH 7.4

Gene Accession No.

O09126, Q92854

Gene Symbols

Sema4d

Immunogen

Recombinant Human SEMA4D protein

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Form

Liquid

Applications

ELISA, Flow Cytometry, Neutralization

Clone

5D12

Conjugate

Unconjugated

Gene

Sema4d

Gene Alias

A8, BB18, C9orf164, CD100, coll-4, GR3, M-Sema G, M-sema-G, sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D, sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, 4D, sema J, Sema4d, Semacl2, SEMAJ, semaphorin 4D, semaphorin H, semaphorin-4D, Semaphorin-C-like 2, semaphorin-J, Semcl2

Host Species

Human

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

10507, 20354

Content And Storage

-20°C or -80°C if preferred

Isotype

IgG4

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Description

  • Semaphorins are neuronal chemorepellants that direct pioneering neurons during nervous system development
  • CD100 (also known as semaphorin 4d), a 150 kDa homodimer, is a novel semaphorin that induces B cells to aggregate and improves their viability in vitro
  • CD100 modifies CD40-CD40L B cell signaling by augmenting B cell aggregation and survival and down regulating CD23 expression
  • CD72 is a lymphocyte receptor for the class IV semaphorin CD100, which is involved in regulating B cell signaling
  • CD100 is expressed on resting and PHA stimulated T cells
  • The protein is weakly expressed on NK cells, EBV transformed B cells, monocytes and tumor/peripheral blood T cell lines, and at higher density on activated T cells and B cells.