Complement C5 Recombinant Mouse Monoclonal Antibody (13H2), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | FEMA550258-Each-of-1 | In Stock | ₹ 37,202.00 |
FEMA550258 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 37,202.00
GST (18%): ₹ 6,696.36
Total Price: ₹ 43,898.36
Antigen
Complement C5
Classification
Recombinant Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.03% Proclin 300, pH 7.4
Gene Accession No.
P01031
Gene Symbols
C5
Immunogen
Recombinant Human C5 protein
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Form
Liquid
Applications
ELISA, Flow Cytometry
Clone
13H2
Conjugate
Unconjugated
Gene
C5
Gene Alias
anaphylatoxin, anaphylatoxin C5, anaphylatoxin C5a analog, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4, C5, C5a, C5a anaphylatoxin, C5b, C5D, Complement C5, Complement C5 alpha chain, Complement C5 alpha' chain, Complement C5 beta chain, complement component 5, CPAMD4, ECLZB, Hc, He, hemolytic complement, prepro-C5, RGD1561905
Host Species
Mouse
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
727
Content And Storage
-20°C or -80°C if preferred
Isotype
IgG
Related Products
Description
- C5 (Complement C5) is a Protein Coding gene
- Diseases associated with C5 include Complement Component 5 Deficiency and Eculizumab, Poor Response To
- Among its related pathways are GPCR downstream signalling and Acquired partial lipodystrophy / Barraquer-Simons syndrome
- Gene Ontology (GO) annotations related to this gene include signaling receptor binding and endopeptidase inhibitor activity
- An important paralog of this gene is C3
- This gene encodes a component of the complement system, a part of the innate immune system that plays an important role in inflammation, host homeostasis, and host defense against pathogens
- The encoded preproprotein is proteolytically processed to generate multiple protein products, including the C5 alpha chain, C5 beta chain, C5a anaphylatoxin and C5b
- The C5 protein is comprised of the C5 alpha and beta chains, which are linked by a disulfide bridge
- Cleavage of the alpha chain by a convertase enzyme results in the formation of the C5a anaphylatoxin, which possesses potent spasmogenic and chemotactic activity, and the C5b macromolecular cleavage product, a subunit of the membrane attack complex (MAC)
- Mutations in this gene cause complement component 5 deficiency, a disease characterized by recurrent bacterial infections
- Alternative splicing results in multiple transcript variants.