FEMA550029

JNK3 Recombinant Rabbit Monoclonal Antibody (29E10), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 FEMA550029-Each-of-1 In Stock ₹ 37,202.00

FEMA550029 - Each of 1

₹ 37,202.00

In Stock

Quantity

1

Base Price: ₹ 37,202.00

GST (18%): ₹ 6,696.36

Total Price: ₹ 43,898.36

Antigen

JNK3

Classification

Recombinant Monoclonal

Concentration

0.25 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.

P53779, Q61831

Gene Symbols

MAPK10

Immunogen

A synthesized peptide derived from human MAPK10

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Form

Liquid

Applications

ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone

29E10

Conjugate

Unconjugated

Gene

MAPK10

Gene Alias

C230008H04Rik, c-Jun N-terminal kinase 3, hypothetical protein LOC569698, jnk3, JNK3 alpha protein kinase, JNK3 beta1 protein kinase, JNK3 beta2 protein kinase, JNK3A, JNK3B1, JNK3B2, MAP kinase 10, MAP kinase p49 3F12, MAPK 10, MAPK10, mitogen activated protein kinase 10, mitogen-activated protein kinase 10, OTTHUMP00000161181, OTTHUMP00000161183, OTTHUMP00000218718, p493F12, p54-beta, p54bSAPK, PRKM10, SAPb, SAPK(beta), SAPK/Erk/kinase 2, SAPK1B, SAPK-beta, SAPKC, Serk2, Stress activated protein kinase beta, stress-activated protein kinase 1b, Stress-activated protein kinase JNK3, zgc:123234

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

26414, 5602

Content And Storage

-20°C or -80°C if preferred

Isotype

IgG

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Description

  • MAPK10 (JNK3) is a neuronal-specific form of c-Jun N-terminal kinases (JNKs)
  • MAPK10 is involved in neuronal apoptosis and phosphorylates MAP2K4
  • MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development
  • This protein is a neuronal-specific form of c-Jun N-terminal kinases (JNKs)
  • Through its phosphorylation and nuclear localization, this kinase plays regulatory roles in the signaling pathways during neuronal apoptosis
  • Beta-arrestin 2, a receptor-regulated MAP kinase scaffold protein, is found to interact with, and stimulate the phosphorylation of this kinase by MAP kinase kinase 4 (NhpK4)
  • Cyclin-dependent kianse 5 can phosphorylate, and inhibit the activity of this kinase, which may be important in preventing neuronal apoptosis
  • Four alternatively spliced transcript variants encoding distinct isoforms have been reported.