PKN2 Recombinant Rabbit Monoclonal Antibody (11H3), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | FEMA550169-Each-of-1 | In Stock | ₹ 37,202.00 |
FEMA550169 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 37,202.00
GST (18%): ₹ 6,696.36
Total Price: ₹ 43,898.36
Antigen
PKN2
Classification
Recombinant Monoclonal
Concentration
2.5 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4
Gene Accession No.
Q16513
Gene Symbols
PKN2
Immunogen
A synthesized peptide derived from Human PKN2
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Form
Liquid
Applications
ELISA, Flow Cytometry, Western Blot
Clone
11H3
Conjugate
Unconjugated
Gene
PKN2
Gene Alias
6030436C20Rik, AI507382, cardiolipin-activated protein kinase Pak2, p140 kinase, PAK2, Pak-2, PKN gamma, PKN2, PRK2, PRKCL2, PRO2042, protease-activated kinase 2, protein kinase C-like 2, protein kinase N2, protein-kinase C-related kinase 2, RP5-905H16.1, serine/threonine kinase 7, serine/threonine-protein kinase N2, serine/threonine-protein kinase N2, serine/threonine-protein kinase N2-like, si:ch211-83f14.1, Stk7, wu:fa97c07
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
5586
Content And Storage
-20°C or -80°C if preferred
Isotype
IgG
Related Products
Description
- PKN2 (PRK2), a close relative of the PKCs, is a regulator of mitosis and exit from cytokinesis
- Plays a role in the regulation of cell cycle progression, actin cytoskeleton assembly, cell migration, cell adhesion, tumor cell invasion and transcription activation signaling processes
- Phosphorylates CTTN in hyaluronan-induced astrocytes and hence decreases CTTN ability to associate with filamentous actin
- Phosphorylates HDAC5, therefore lead to impair HDAC5 import
- Direct RhoA target required for the regulation of the maturation of primordial junctions into apical junction formation in bronchial epithelial cells
- Required for G2/M phases of the cell cycle progression and abscission during cytokinesis in a ECT2-dependent manner
- Stimulates FYN kinase activity that is required for establishment of skin cell-cell adhesion during keratinocytes differentiation
- Regulates epithelial bladder cells speed and direction of movement during cell migration and tumor cell invasion
- Inhibits Akt pro-survival-induced kinase activity
- Mediates Rho protein-induced transcriptional activation via the c-fos serum response factor (SRF)
- Phosphorylates HCV NS5B leading to stimulation of HCV RNA replication.