LRP2 Recombinant Rabbit Monoclonal Antibody (10B5), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | FEMA550033-Each-of-1 | In Stock | ₹ 37,202.00 |
FEMA550033 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 37,202.00
GST (18%): ₹ 6,696.36
Total Price: ₹ 43,898.36
Antigen
LRP2
Classification
Recombinant Monoclonal
Concentration
3 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4
Gene Accession No.
P98164
Gene Symbols
Lrp2
Immunogen
A synthesized peptide derived from human LRP2
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Form
Liquid
Applications
ELISA, Flow Cytometry
Clone
10B5
Conjugate
Unconjugated
Gene
Lrp2
Gene Alias
AI315343, AW536255, b2b1625.2Clo, calcium sensor protein, D230004K18Rik, DBS, Glycoprotein 330, Gp330, Heymann nephritis antigen homolog, LDL receptor related protein 2, low density lipoprotein receptor-related protein 2, low density lipoprotein-related protein 2, low-density lipoprotein receptor-related protein 2, Lrp2, LRP-2, Megalin
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
4036
Content And Storage
-20°C or -80°C if preferred
Isotype
IgG
Related Products
Description
- The protein encoded by this gene, low density lipoprotein-related protein 2 (LRP2) or megalin, is a multi-ligand endocytic receptor that is expressed in many different tissues but primarily in absorptive epithilial tissues such as the kidney
- This glycoprotein has a large amino-terminal extracellular domain, a single transmembrane domain, and a short carboxy-terminal cytoplasmic tail
- The extracellular ligand-binding-domains bind diverse macromolecules including albumin, apolipoproteins B and E, and lipoprotein lipase
- The LRP2 protein is critical for the reuptake of numerous ligands, including lipoproteins, sterols, vitamin-binding proteins, and hormones
- This protein also has a role in cell-signaling; extracellular ligands include parathyroid horomones and the morphogen sonic hedgehog while cytosolic ligands include MAP kinase scaffold proteins and JNK interacting proteins
- Recycling of this membrane receptor is regulated by phosphorylation of its cytoplasmic domain
- Mutations in this gene cause Donnai-Barrow syndrome (DBS) and facio-oculoacoustico-renal syndrome (FOAR).