Transferrin Receptor Recombinant Human Monoclonal Antibody (7H12), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | FEMA550098-Each-of-1 | In Stock | ₹ 37,202.00 |
FEMA550098 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 37,202.00
GST (18%): ₹ 6,696.36
Total Price: ₹ 43,898.36
Antigen
Transferrin Receptor
Classification
Recombinant Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.03% Proclin 300, pH 7.4
Gene Accession No.
P02786
Gene Symbols
TFRC
Immunogen
Recombinant Human TFRC protein
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Form
Liquid
Applications
ELISA, Neutralization
Clone
7H12
Conjugate
Unconjugated
Gene
TFRC
Gene Alias
2610028K12Rik, AI195355, AI426448, AU015758, CD antigen CD71, CD71, chicken transferrin receptor, E430033M20Rik, I79_000642, IMD46, mammary tumor virus receptor 1, Mtvr1, Mtvr-1, p90, sTfR, T9, TfR, tfR1, TFR2, TFRC, TR, transferrin receptor, transferrin receptor (p90, CD71), transferrin receptor 2, transferrin receptor protein 1, Transferrin receptor protein 1, serum form, Trfr
Host Species
Human
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
7037
Content And Storage
-20°C or -80°C if preferred
Isotype
IgG1
Related Products
Description
- Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes
- Endosomal acidification leads to iron release
- The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor
- Transferrin receptor is necessary for development of erythrocytes and the nervous system
- Serum transferrin receptor (sTfR) is used as a means of detecting erythropoietin (EPO) misuse by athletes and as a diagnostic test for anemias resulting from a number of conditions including rheumatoid arthritis, pregnancy, irritable bowel syndrome and in HIV patients.