FEMA550166

NAIP Recombinant Rabbit Monoclonal Antibody (13E6), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 FEMA550166-Each-of-1 In Stock ₹ 37,202.00

FEMA550166 - Each of 1

₹ 37,202.00

In Stock

Quantity

1

Base Price: ₹ 37,202.00

GST (18%): ₹ 6,696.36

Total Price: ₹ 43,898.36

Antigen

NAIP

Classification

Recombinant Monoclonal

Concentration

1.03 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.

Q13075

Gene Symbols

NAIP

Immunogen

A synthesized peptide derived from Human NAIP

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

Applications

ELISA, Immunohistochemistry (Paraffin)

Clone

13E6

Conjugate

Unconjugated

Gene

NAIP

Gene Alias

AV364616, baculoviral IAP repeat-containing 1a, baculoviral IAP repeat-containing protein 1, Baculoviral IAP repeat-containing protein 1a, BIRC1, Birc1a, D13Lsd1, FLJ18088, FLJ42520, FLJ58811, Naip, Naip1, Naip-rs1, Neuronal apoptosis inhibitory protein, neuronal apoptosis inhibitory protein 1, NLR family apoptosis inhibitory protein, NLR family, apoptosis inhibitory protein, NLR family, apoptosis inhibitory protein 1, NLRB1, nucleotide-binding oligomerization domain, leucine rich repeat and BIR domain containing 1, psi neuronal apoptosis inhibitory protein, psiNAIP

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

4671

Content And Storage

-20°C or -80°C if preferred

Isotype

IgG

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Description

  • Neuronal apoptosis inhibitor protein (NAIP) was the first human inhibitor of apoptosis protein (IAP) identified and was discovered by its association with the neurodegenerative disorder spinal muscular atrophy
  • Members of the IAP family contain one to three copies of an approximately 70 amino acid motif termed baculovirus IAP repeat (BIR); these BIRs promote protein-protein interactions with various caspases such as caspase-3, -7, and -9 as well as members of the TRAF family of signal molecules (reviewed in 3)
  • Unlike other IAPs however, NAIP requires ATP to bind caspase-9 and is not inhibited by the IAP-inhibiting molecule Smac/DIABLO, suggesting that NAIP is unique among the IAPs in its regulation of its activity
  • Finally, although only one human NAIP protein has been identified, other shorter NAIP mRNA transcripts have been reported.