PI3K p85 alpha Recombinant Rabbit Monoclonal Antibody (13E7), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | FEMA550187-Each-of-1 | In Stock | ₹ 37,202.00 |
FEMA550187 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 37,202.00
GST (18%): ₹ 6,696.36
Total Price: ₹ 43,898.36
Antigen
PI3K p85 alpha
Classification
Recombinant Monoclonal
Concentration
1.5 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4
Gene Accession No.
P27986
Gene Symbols
PIK3R1
Immunogen
A synthesized peptide derived from Human PIK3R1
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Form
Liquid
Applications
ELISA, Immunohistochemistry (Paraffin)
Clone
13E7
Conjugate
Unconjugated
Gene
PIK3R1
Gene Alias
AGM7, GRB1, IMD36, p50alpha, p55alpha, p55-GAMMA, p55PIK, p85, p85alpha, p85-ALPHA, phosphatidylinositol 3-kinase, phosphatidylinositol 3-kinase 55 kDa regulatory subunit gamma, phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha, Phosphatidylinositol 3-kinase regulatory subunit alpha, phosphatidylinositol 3-kinase regulatory subunit gamma, phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha), phosphatidylinositol 3-kinase-associated p-85 alpha, Phosphoinositide 3-kinase p85 (other splicing variants: p55 and p50), Phosphoinositide 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha), phosphoinositide-3-kinase regulatory subunit, phosphoinositide-3-kinase regulatory subunit 1, phosphoinositide-3-kinase regulatory subunit alpha, phosphoinositide-3-kinase, regulatory subunit 1 (alpha), phosphoinositide-3-kinase, regulatory subunit 1 (p85 alpha), phosphoinositide-3-kinase, regulatory subunit, polypeptide 1 (p85 alpha), PI3K, PI3K regulatory subunit alpha, PI3K regulatory subunit gamma, PI3KA, PI3-kinase p85 subunit alpha, PI3-kinase p85-subunit alpha, PI3-kinase regulatory subunit alpha, PI3-kinase regulatory subunit gamma, PI3-kinase subunit p55-gamma, PI3-kinase subunit p85-alpha, Pik3r1, polypeptide 1 p85 alpha, ptdIns-3-kinase p85-alpha, ptdIns-3-kinase regulatory subunit alpha, PtdIns-3-kinase regulatory subunit p85-al, ptdIns-3-kinase regulatory subunit p85-alpha, RP4-533D7.2
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
5295
Content And Storage
-20°C or -80°C if preferred
Isotype
IgG
Related Products
Description
- Phosphatidylinositol 3-kinase (PIK3) is a signaling protein that phosphorylates the inositol ring of phosphatidylinositol at the 3-prime position
- Signaling is initiated when upstream tyrosine kinase receptors or G protein coupled receptors are bound by their ligands
- It binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane
- Phosphatidylinositol 3-kinase plays an important role in the metabolic actions of insulin, and a mutation in this gene has been associated with insulin resistance
- During insulin stimulation, it also binds to IRS-1
- Mutations in the gene can result in Agammaglobulinemia 7, SHORT syndrome, or Immunodeficiency 36.