FEMA550308

TET1 Monoclonal Antibody (GT2457), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 FEMA550308-Each-of-1 In Stock ₹ 40,851.00

FEMA550308 - Each of 1

₹ 40,851.00

In Stock

Quantity

1

Base Price: ₹ 40,851.00

GST (18%): ₹ 7,353.18

Total Price: ₹ 48,204.18

Antigen

TET1

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 20% glycerol and no preservative

Gene Accession No.

Q8NFU7

Gene Symbols

TET1

Immunogen

Recombinant protein encompassing a sequence within the center region of human TET1. The exact sequence is proprietary.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

Applications

Western Blot

Clone

GT2457

Conjugate

Unconjugated

Gene

TET1

Gene Alias

2510010B09Rik, AA517754, bA119F7.1, BB001228, CXXC finger 6, CXXC zinc finger 6, CXXC6, CXXC-type zinc finger protein 6, D10Ertd17e, KIAA1676, LCX, leukemia-associated protein with a CXXC domain, Methylcytosine dioxygenase TET1, mKIAA1676, MLL-TET1, RP11-119F7.1, Ten-eleven translocation 1 gene protein, ten-eleven translocation 1 gene protein homolog, ten-eleven translocation-1, tet methylcytosine dioxygenase 1, tet oncogene 1, Tet1, TET1 splice variant VP_DE4, TET1 splice variant VP_DE456, TET1-MLL

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

80312

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype

IgG1

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Description

  • Dioxygenase that specifically binds methylcytosine (5mC), a minor base in mammalian DNA found in repetitive DNA elements that is crucial for retrotransposon silencing and mammalian development
  • Catalyzes the conversion of methylcytosine (5mC) to 5-hydroxymethylcytosine (hmC)
  • The clear function of 5-hydroxymethylcytosine (hmC) is still unclear but it may influence chromatin structure and recruit specific factors or may constitute an intermediate component in cytosine demethylation
  • 5-hydroxymethylcytosine (hmC) is present in ES cells and is enriched in the brain, especially in Purkinje neurons
  • May play a role in the fetal development of heart, lung and brain.