FEMA550322

HSP70 Recombinant Rabbit Monoclonal Antibody (HL1581), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 FEMA550322-Each-of-1 In Stock ₹ 41,385.00

FEMA550322 - Each of 1

₹ 41,385.00

In Stock

Quantity

1

Base Price: ₹ 41,385.00

GST (18%): ₹ 7,449.30

Total Price: ₹ 48,834.30

Antigen

HSP70

Classification

Recombinant Monoclonal

Concentration

1 mg/mL

Formulation

PBS with no preservative

Gene Accession No.

P0DMV8, P0DMV9, P34931, P34932, P54652

Gene Symbols

HSPA1A, HSPA1B, Hspa1l, HSPA2, HSPA4

Immunogen

Recombinant protein encompassing a sequence within the center region of human Hsp70. The exact sequence is proprietary.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Feline, Human

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Clone

HL1581

Conjugate

Unconjugated

Gene

HSPA2

Gene Alias

68 kDa heat shock protein, 70 kda heat shock protein-2, 70 kilodalton heat shock protein, 87A, 87A locus, 87C locus, Bb, CG18743, CG31359, CG31359-PA, CG31366, CG31366-PA, CG31449, CG6489, chaperone, dHSP70, dhsp70Aa, Dmel\CG31359, Dmel\CG31366, Dmel_CG31359, Dmel_CG31366, Dm-hsp70, DmHSP70AA, DMHSP7D1, dnaK-type molecular chaperone HSP70-1, epididymis secretory protein Li 103, Hcp70.1, heat shock 10kDa protein 1-like, heat shock 70, heat shock 70 kD protein 1, heat shock 70 kD protein 2, heat shock 70 kDa protein 1, heat shock 70 kDa protein 1/2, heat shock 70 kDa protein 1A, heat shock 70 kDa protein 1A/1B, heat shock 70 kDa protein 1B, Heat shock 70 kDa protein 1-Hom, Heat shock 70 kDa protein 1L, heat shock 70 kDa protein 1-like, heat shock 70 kDa protein 2, Heat shock 70 kDa protein 3, heat shock 70 kDa-like protein 1, heat shock 70kD protein 1A, heat shock 70kD protein 1B, heat shock 70kD protein 1B (mapped), heat shock 70kD protein-like 1, heat shock 70kDa protein 1A, heat shock

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

101088003, 101097784, 3303, 3304, 3305, 3306, 3308

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype

IgG

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Description

  • HSP70 is a Heat shock protein (HSP) which are expressed in response to various biological stresses, including high temperatures
  • There are several major families of HSPs that include HSP70, there are HSP90 and HSP100
  • The HSP70 family is a set of highly conserved proteins that are induced by a variety of biological stresses, including heat stress, in every organism in which the proteins have been examined
  • The human HSP70 family members include: HSP70, a protein which is strongly inducible in all organisms but which is also constitutively expressed in primate cells; HSP72, a 72 kDa protein that is induced exclusively under stress conditions; HSC70, or cognate protein, is a 72 kDa, constitutively expressed, protein which is involved in the uncoating of clathrin coated vesicles; GRP78, or BiP, is a glucose regulated 78 kDa protein localized in the endoplasmic reticulum; and p75, or HSP75, a 75 kDa protein that is found within the mitochondria
  • Further, HSP70 is encoded by an intronless gene and, in conjunction with other heat shock proteins, HSP70 stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and organelles
  • HSP70 is also involved in the ubiquitin-proteasome pathway through interaction with the AU-rich element RNA-binding protein 1
  • The HSP70 gene is located in the major histocompatibility complex class III region, in a cluster with two closely related genes which encode similar proteins.