FEMA550395

Pepsinogen I Recombinant Rabbit Monoclonal Antibody (HL2137), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 FEMA550395-Each-of-1 In Stock ₹ 41,385.00

FEMA550395 - Each of 1

₹ 41,385.00

In Stock

Quantity

1

Base Price: ₹ 41,385.00

GST (18%): ₹ 7,449.30

Total Price: ₹ 48,834.30

Antigen

Pepsinogen I

Classification

Recombinant Monoclonal

Concentration

1 mg/mL

Formulation

PBS with no preservative

Gene Accession No.

P0DJD9, Q9D106

Gene Symbols

Pga5

Immunogen

Recombinant fragmemt of human Pepsinogen I.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Form

Liquid

Applications

ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone

HL2137

Conjugate

Unconjugated

Gene

Pga5

Gene Alias

1110035E17Rik, Pepf, pepsin A, pepsin A-3, Pepsin A-5, Pepsin F, pepsinogen 3, group I (pepsinogen A), pepsinogen 5, group I, pepsinogen 5, group I (pepsinogen A), pepsinogen A3, pepsinogen A5, pepsinogen F, pepsinogen F protein, pepsinogen-3, Pepsinogen-5, Pg5, PGA3, PGA5

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

5222, 58803, 60372

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype

IgG

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Description

  • MA5-50395 has sucessfully been used in Indirect ELISA
  • PGA5: Pepsinogen 5, group I (pepsinogen A)
  • Pepsinogens are the inactive precursors of pepsin, the major acid protease found in the stomach
  • Pepsin is one of the main proteolytic enzymes secreted by the gastric mucosa
  • Pepsin consists of a single polypeptide chain and arises from its precursor, pepsinogen, by removal of a 41 amino acid segment from the N-terminus
  • Pepsinogen is synthesized in the stomach lining, and hydrochloric acid, also produced by the gastric mucosa, is necessary to convert the inactive enzyme and to maintain the optimum acidity (pH 1-3) for pepsin function
  • Pepsin is particularly effective in cleaving peptide bonds involving aromatic amino acids
  • Pepsin shows extremely broad specificity; although bonds involving phenylalanine and leucine are preferred, many others are also cleaved to some extent
  • PGA5 is a member of the subfamily A1 within the pepsin family and is the predominant endopeptidase in the gastric juice of vertebrates
  • PGA5 is inhibited by ovUS-1, a uterine serpin.