FEMA550474

Glutamine Synthetase Recombinant Rabbit Monoclonal Antibody (HL2283), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 FEMA550474-Each-of-1 In Stock ₹ 41,385.00

FEMA550474 - Each of 1

₹ 41,385.00

In Stock

Quantity

1

Base Price: ₹ 41,385.00

GST (18%): ₹ 7,449.30

Total Price: ₹ 48,834.30

Antigen

Glutamine Synthetase

Classification

Recombinant Monoclonal

Concentration

1 mg/mL

Formulation

PBS with no preservative

Gene Accession No.

P09606, P15104, P15105, Q8HZM5

Gene Symbols

GLUL

Immunogen

Full length of human Glutamine synthetase.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Canine, Feline, Human, Mouse, Rat

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Clone

HL2283

Conjugate

Unconjugated

Gene

GLUL

Gene Alias

cell proliferation-inducing protein 59, GLNA, GLNS, Glul, GLUL protein, Glutamate ammonia ligase, glutamate decarboxylase, glutamate-ammonia ligase, glutamate--ammonia ligase, glutamate-ammonia ligase (glutamine synthase), glutamate-ammonia ligase (glutamine synthetase), glutamine synthase, glutamine synthetase, Glutamine synthetase (glutamate-ammonia ligase), glutamine synthetase 1, glutamine synthetase I, GS, Palmitoyltransferase GLUL, PIG43, PIG59, Proliferation inducing protein 43, proliferation-inducing protein 43

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

101093325, 14645, 24957, 2752, 403443

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype

IgG

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Description

  • Glutamine synthase is part of the glutamine synthetase family
  • Ammonia incorporation in animals occurs through the actions of glutamate dehydrogenase and glutamine synthase
  • Glutamate plays the central role in mammalian nitrogen flow, serving as both a nitrogen donor and nitrogen acceptor
  • It also has an important role in controlling metabolic regulations of neurotransmitter glutamate
  • Because of the multiple functions and importance of GS in cellular metabolism, both catalytic activities and synthesis are highly regulated
  • The activity of GS is controlled by adenylylation
  • Its activity is decreased in the cerebral cortex of brains affected by Alzheimer's disease, particularly in the vicinity of senile plaques
  • It is also decreased under conditions of glucose deprivation.