GAD67 Recombinant Rabbit Monoclonal Antibody (HL1096), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | FEMA550303-Each-of-1 | In Stock | ₹ 41,385.00 |
FEMA550303 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 41,385.00
GST (18%): ₹ 7,449.30
Total Price: ₹ 48,834.30
Antigen
GAD67
Classification
Recombinant Monoclonal
Concentration
1 mg/mL
Formulation
PBS with no preservative
Gene Accession No.
A0PA85, P14748, P18088, P48318, Q99259
Gene Symbols
GAD1
Immunogen
Recombinant protein encompassing a sequence within the center region of human GAD67. The exact sequence is proprietary.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Canine, Feline, Human, Mouse, Rat
Form
Liquid
Applications
Immunohistochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone
HL1096
Conjugate
Unconjugated
Gene
GAD1
Gene Alias
67 kDa glutamic acid decarboxylase, 67kDa glutamate decarboxylase 1, CPSQ1, EGK_04525, EP10, FLJ45882, GAD, GAD 1, GAD 67, GAD1, Gad-1, GAD25, GAD44, Gad67, GAD-67, Glutamate decarboxylase 1, Glutamate decarboxylase 1 (brain), glutamate decarboxylase 1 (brain, 67kDa), glutamate decarboxylase 1 isoform GAD67, glutamate decarboxylase 1 variant GAD67NT, glutamate decarboxylase 67 kDa isoform, GLUTAMATE DECARBOXYLASE, 67 KD ISOFORM (GAD-67) (67 KD GLUTAMIC ACID DECARBOXYLASE), glutamic acid decarboxylase, glutamic acid decarboxylase 1, glutamic acid decarboxylase isoform 67, OTTHUMP00000041055, SCP
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
14415, 24379, 2571, 478794, 493699
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype
IgG
Related Products
Description
- GAD-65 and GAD-67 are members of the group II decarboxylase family of proteins and are responsible for catalyzing the rate limiting step in the production of GABA (gamma-aminobutyric acid) from L-glutamic acid
- Although both GADs are found in the brain, GAD-65 localizes to synaptic vesicle membranes in nerve terminals, while GAD-67 is distributed throughout the cell
- GAD-67 is responsible for the basal levels of GABA synthesis
- In the case of a heightened demand for GABA in neurotransmission, GAD-65 will transiently activate to assist in GABA production
- The loss of GAD-65 is detrimental and can impair GABA neurotransmission, however the loss of GAD-67 is lethal
- Due to alternative splicing, two isoforms exist for GAD-67: the predominant GAD-67 form and the minor GAD-25 form.